Understanding the Synthesis and Properties of Diacetone-D-glucose
NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing high-quality chemical intermediates, including Diacetone-D-glucose (CAS 582-52-5). This compound, a protected form of D-glucose, is synthesized by reacting D-glucose with acetone in the presence of an acid catalyst, typically sulfuric acid. This reaction selectively protects the hydroxyl groups at the 1,2 and 5,6 positions with isopropylidene ketals, yielding the stable, crystalline Diacetone-D-glucose. The resulting product usually appears as a white to yellow powder.
The synthesis process is carefully controlled to ensure high purity, often exceeding 99%, which is critical for its demanding applications. Understanding the diacetone-d-glucose molecular formula (C12H20O6) and its molecular weight (260.29 g/mol) is fundamental for chemists working with this intermediate. The presence of the isopropylidene groups renders the 1,2 and 5,6 hydroxyls inert to many reactions, while the free hydroxyl at the C-3 position remains available for further functionalization. This selective protection is the key to its utility.
Diacetone-D-glucose exhibits good stability when stored correctly, ideally in a cool, ventilated place, and is typically associated with a shelf life of two years. Its solubility in common organic solvents like acetone and ethanol further enhances its ease of use in synthesis. NINGBO INNO PHARMCHEM CO.,LTD. ensures that each batch meets stringent quality specifications, making it a reliable choice for those looking to buy Diacetone-D-glucose for their production needs. Its role as a pharmaceutical intermediate and a building block for fine chemicals stems directly from these well-defined properties and controlled synthesis.
The strategic importance of Diacetone-D-glucose in enabling complex chemical pathways underscores the value of sourcing it from reputable suppliers. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential intermediate with the highest standards of quality and consistency, supporting advancements in chemistry and related industries.
Perspectives & Insights
Agile Reader One
“The presence of the isopropylidene groups renders the 1,2 and 5,6 hydroxyls inert to many reactions, while the free hydroxyl at the C-3 position remains available for further functionalization.”
Logic Vision Labs
“Diacetone-D-glucose exhibits good stability when stored correctly, ideally in a cool, ventilated place, and is typically associated with a shelf life of two years.”
Molecule Origin 88
“Its solubility in common organic solvents like acetone and ethanol further enhances its ease of use in synthesis.”