N-(4-Cyanophenyl)guanidine, identified by CAS number 5637-42-3, is a compound of significant interest in the chemical and pharmaceutical industries due to its unique properties and synthetic utility. As a crucial pharmaceutical intermediate, understanding its physical and chemical characteristics is key to its effective application. This article explores these properties and highlights its importance in synthesizing critical drugs.

Chemically, N-(4-Cyanophenyl)guanidine (Molecular Formula: C8H8N4, Molecular Weight: 160.176) is known for its crystalline white appearance. Its melting point typically falls within the range of 155-162°C, with some specifications noting a higher range of 205-215°C, indicating potential variations in crystal form or purity. The compound exhibits good solubility in solvents like DMSO and Methanol, which is advantageous for its use in various organic synthesis reactions. Its assay, often specified as ≥98.0% by HPLC, underscores its suitability for applications demanding high purity, a critical factor when this compound is used as an Etravirine synthesis intermediate.

The primary application of N-(4-Cyanophenyl)guanidine is its role in the synthesis of Etravirine and Rilpivirine, both potent antiviral agents. The specific structure of N-(4-Cyanophenyl)guanidine allows for precise chemical transformations, enabling chemists to build the complex molecular architecture required for these pharmaceuticals. This makes it an indispensable pharmaceutical intermediate CAS 5637-42-3, facilitating the production of essential medicines that combat viral infections.

NINGBO INNO PHARMCHEM CO.,LTD. is a prominent manufacturer and supplier that provides this compound with exceptional purity and reliability. Their capabilities in bulk supply and contract manufacturing ensure that pharmaceutical companies have access to a consistent source of this vital intermediate. For those looking to buy N-(4-Cyanophenyl)guanidine, partnering with a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. guarantees that the material meets stringent quality standards necessary for pharmaceutical applications.

The significance of N-(4-Cyanophenyl)guanidine in drug development cannot be overstated. Its chemical properties make it a versatile tool for chemists engaged in the creation of new therapeutic compounds. Whether for established drugs like Rilpivirine or for novel research projects, the reliable sourcing of high-quality intermediates is fundamental. Therefore, identifying a trusted 4-Guanidinobenzonitrile supplier like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for successful drug synthesis and innovation.