The world of chemistry is built upon a foundation of specific molecules, each with unique properties that dictate its utility. 5-chloro-3-nitropyrazolo[1,5-a]pyrimidine, bearing the CAS number 1363380-51-1, is a prime example of such a compound. Its structure, characterized by a fused pyrazolo and pyrimidine ring system with chloro and nitro substituents, imbues it with reactivity that is highly sought after in specialized chemical applications, particularly within the pharmaceutical sector.

As a white powder with a minimum purity of 97%, 5-chloro-3-nitropyrazolo[1,5-a]pyrimidine is primarily recognized for its role as a pharmaceutical intermediate. This designation means it is a precursor in the multistep synthesis of complex drug molecules. Its specific chemical features make it an ideal starting point for building more elaborate structures. For instance, it is a vital component in the synthesis of Larotrectinib, an important targeted therapy for cancers characterized by NTRK gene fusions. The successful synthesis of such drugs relies on the consistent quality and precise chemical reactivity of intermediates like 5-chloro-3-nitropyrazolo[1,5-a]pyrimidine.

The compound's significance extends into the broader field of organic chemistry. It can function as a valuable synthon – a structural unit within a molecule that can be formed or assembled by known synthetic reactions. This makes it a tool for chemists to construct intricate organic frameworks. Whether used as a reagent or a building block, its predictable chemical behavior allows for the design of efficient synthetic pathways, contributing to advancements in materials science and other chemical disciplines. Exploring different reaction conditions and combinations can unlock novel applications for this versatile chemical.

Furthermore, the presence of both a halogen (chlorine) and a nitro group on the heterocyclic core suggests potential for various chemical modifications. These functional groups can be selectively reacted to introduce other chemical entities, further expanding the synthetic utility of 5-chloro-3-nitropyrazolo[1,5-a]pyrimidine. The ability to perform regioselective or chemoselective transformations on this molecule is key to its value in complex synthesis projects.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying researchers and manufacturers with high-grade 5-chloro-3-nitropyrazolo[1,5-a]pyrimidine. We understand the critical nature of these intermediates in driving scientific innovation and drug development. Our commitment to quality assurance means that clients can depend on us for materials that meet stringent purity requirements, crucial for reproducible results and the successful scaling up of chemical processes. Trust in our expertise to provide the foundational chemicals that power your laboratory's breakthroughs.

In summary, the chemical structure and properties of 5-chloro-3-nitropyrazolo[1,5-a]pyrimidine (CAS 1363380-51-1) position it as a vital intermediate in pharmaceutical synthesis and a versatile tool in organic chemistry. Its contribution to the development of advanced therapies and its utility in complex synthetic endeavors highlight its importance in the chemical industry. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a supplier of this essential compound, supporting the advancement of science and medicine.