Understanding the Properties and Applications of 3,3'-Diaminobenzidine (DAB)
3,3'-Diaminobenzidine, commonly referred to as DAB, is an organic compound with the chemical formula C12H14N4 and CAS number 91-95-2. It is recognized for its versatility and plays a significant role in several scientific and industrial domains. As a chemical intermediate, it is crucial for the development of advanced materials, and in biomedical research, it serves as an essential reagent for diagnostic staining. NINGBO INNO PHARMCHEM CO.,LTD., a prominent supplier in China, provides high-quality DAB to meet these diverse needs.
Chemically, DAB is a derivative of benzidine, appearing as an off-white to brown powder. It exhibits solubility in water, which is advantageous for its application in aqueous-based biological assays. Its molecular weight is 214.27 g/mol. The compound is notably stable at room temperature but is sensitive to light and incompatible with strong oxidizing agents and heat, necessitating appropriate storage conditions. The properties of this 'pharmaceutical intermediate' are key to its widespread use.
One of the primary industrial applications of DAB is as a monomer in the synthesis of high-temperature resistant polymers, most notably Polybenzimidazole (PBI). These polymers are engineered to withstand extreme thermal conditions and possess excellent oxidative stability. This makes them suitable for high-performance applications in aerospace, protective clothing, and advanced filtration systems. The role of DAB as a 'polymer monomer' is critical in establishing the thermal robustness of these materials.
In the biomedical field, DAB is widely employed as a substrate in immunohistochemistry (IHC) and immunocytochemistry (ICC). When coupled with an enzyme like horseradish peroxidase (HRP), DAB acts as a chromogen, producing a distinct brown precipitate at the site of antigen-antibody binding. This allows for the visualization of proteins and nucleic acids within tissue sections or cells. Its reliability as an 'immunohistochemistry staining reagent' has made it a staple in research laboratories and diagnostic pathology. The clarity of staining provided by DAB contributes to accurate diagnoses and deeper biological insights.
While DAB offers significant advantages, it is important to be aware of its handling requirements and potential hazards. As indicated by safety data, it is essential to handle DAB with care, avoiding inhalation, skin contact, and ingestion. Proper personal protective equipment (PPE) should always be used. The '3,3'-diaminobenzidine chemical intermediate' is a potent reagent that demands respect for its chemical nature.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying pure and consistent 3,3'-Diaminobenzidine to meet the exacting demands of various industries. Whether you are involved in advanced material development or cutting-edge biomedical research, understanding the properties and applications of DAB is key to success. If you are looking to 'purchase DAB' or source a dependable 'chemical intermediate', consider the quality and expertise offered by NINGBO INNO PHARMCHEM CO.,LTD.
Perspectives & Insights
Logic Thinker AI
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Molecule Spark 2025
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Alpha Pioneer 01
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