While Citiolone (CAS 17896-21-8) is recognized for its therapeutic benefits, particularly in liver therapy and as a mucolytic agent, understanding its side effects and safety profile is crucial for responsible clinical application. NINGBO INNO PHARMCHEM CO.,LTD. provides essential information regarding the safety of this chemical compound.

Citiolone, chemically known as DL-N-Acetylhomocysteine thiolactone, is generally considered to have a low toxicity profile, largely due to its nature as a derivative of naturally occurring cysteine. However, like most pharmaceutical agents, it can cause adverse reactions in a subset of individuals. The most commonly reported side effect is a fixed-drug eruption, a type of allergic reaction where a specific skin lesion reappears in the same location upon re-exposure to the drug. Cases have documented pruritic erythema and blistering followed by macules at the site of previous lesions after oral intake and patch testing.

It is important to note that while such reactions are documented, they are considered rare. The incidence of fixed-drug eruption from mucolytic drugs, including Citiolone, has been reported, but these instances are not widespread. Healthcare professionals often conduct patch testing to identify potential sensitivities. For patients who experience such reactions, discontinuation of the medication is typically recommended.

Beyond dermatological reactions, other reported side effects are generally mild and infrequent. These can include headaches, nausea, stomach pain, diarrhea, or constipation. Research suggests that Citiolone may also interact with certain medications, such as levodopa, a drug used to treat Parkinson's disease. Therefore, it is imperative for patients to disclose all medications they are currently taking to their healthcare provider before commencing treatment with Citiolone.

NINGBO INNO PHARMCHEM CO.,LTD. supplies Citiolone primarily for research and industrial purposes, adhering to strict quality control measures to ensure product purity and consistency. While the company provides the chemical, its clinical application and management of side effects fall under the purview of medical professionals.

The study of Citiolone for liver therapy and its other applications often includes safety assessments. While the compound is valued for its Citiolone hepatoprotective effects and its role as a hydroxyl free radical scavenger, awareness of potential adverse reactions is paramount. The reported incidence of side effects, such as fixed-drug eruption, necessitates careful patient monitoring and informed consent.

In summary, while Citiolone possesses valuable therapeutic properties, including its antioxidant functions and its use as a mucolytic agent, potential side effects must be considered. NINGBO INNO PHARMCHEM CO.,LTD. ensures the quality of the chemical, supporting the safe and informed use of Citiolone in its intended applications.