NINGBO INNO PHARMCHEM CO.,LTD. is proud to offer tert-Butyl 3-oxoazetidine-1-carboxylate, a compound distinguished by its robust chemical properties and significant applications within the pharmaceutical sector. With the CAS number 398489-26-4, this molecule, also known as N-Boc-3-oxoazetidine, serves as a critical pharmaceutical intermediate essential for the synthesis of complex APIs. Its utility is particularly pronounced in the production of Baricitinib, a key therapeutic agent for autoimmune conditions.

The intrinsic value of tert-Butyl 3-oxoazetidine-1-carboxylate is rooted in its physical and chemical characteristics. Exhibiting an assay purity of ≥98.0%, it guarantees a high degree of reliability for sensitive downstream processes. Physically, it presents as off-white crystals, with a defined melting point range of 49-52°C. Its density is approximately 1.2±0.1 g/cm³, and it has a boiling point of 251.3±33.0 °C at 760 mmHg. These properties indicate a compound that is stable under typical handling and storage conditions, yet possesses the necessary reactivity for complex chemical transformations. This balance is crucial for its role as an azetidine derivative in drug synthesis.

The primary application of tert-Butyl 3-oxoazetidine-1-carboxylate is its function as a building block for Baricitinib, a Janus kinase (JAK) inhibitor. Baricitinib’s efficacy in treating rheumatoid arthritis and other autoimmune disorders highlights the importance of its precursors. The azetidine ring, protected by the Boc group, provides a versatile framework that chemists can manipulate to achieve the precise molecular architecture required for therapeutic activity. This makes the compound a highly sought-after intermediate for Baricitinib manufacturing. For those seeking to purchase tert-Butyl 3-oxoazetidine-1-carboxylate, understanding these applications is key to appreciating its value.

NINGBO INNO PHARMCHEM CO.,LTD. leverages advanced synthetic techniques to produce tert-Butyl 3-oxoazetidine-1-carboxylate, meeting the stringent purity and quality demands of the global pharmaceutical market. As a prominent tert-Butyl 3-oxoazetidine-1-carboxylate manufacturer in China, we ensure that our product aligns with international benchmarks. We offer flexible packaging solutions, typically in 25 kg drums, tailored to meet diverse customer needs, from research laboratories to large-scale production facilities. Storing the compound in a cool, ventilated environment is recommended to maintain its integrity.

The role of this compound in creating JAK inhibitor synthesis building blocks is expanding as research into autoimmune diseases progresses. Its well-defined chemical structure and predictable reactivity make it an ideal starting material for creating novel chemical entities. Pharmaceutical research and development teams worldwide rely on a consistent supply of high-quality intermediates to drive innovation. By providing reliable access to tert-Butyl 3-oxoazetidine-1-carboxylate, NINGBO INNO PHARMCHEM CO.,LTD. supports these critical efforts.

For organizations interested in sourcing high-quality pharmaceutical intermediates, particularly tert-Butyl 3-oxoazetidine-1-carboxylate, NINGBO INNO PHARMCHEM CO.,LTD. is a trusted partner. We are dedicated to supporting the pharmaceutical industry with top-tier chemical solutions. Contact us today to learn more about how we can meet your specific requirements for this vital chemical compound.