The Synthesis and Chemical Properties of Bis(2-ethylhexyl) Sebacate
Understanding the synthesis and fundamental chemical properties of key industrial chemicals is crucial for effective application and development. NINGBO INNO PHARMCHEM CO.,LTD. delves into the intricacies of Bis(2-ethylhexyl) Sebacate (DOS), a vital diester with diverse industrial uses, examining its production pathways and inherent characteristics.
The synthesis of Bis(2-ethylhexyl) Sebacate primarily involves the esterification reaction between sebacic acid and 2-ethylhexanol. This process can be achieved through several methods, each with its own set of advantages. Traditional acid catalysis, often employing sulfuric acid or p-toluenesulfonic acid, is a widely used industrial technique. These methods typically require elevated temperatures and careful control of reaction conditions to achieve high yields of the diester. The mechanism involves the protonation of the carboxylic acid group, facilitating nucleophilic attack by the alcohol.
More advanced synthesis routes include non-catalytic high-pressure methods where sebacic acid itself acts as a catalyst at significantly high temperatures and pressures. This approach eliminates the need for external catalysts, simplifying the process and potentially reducing environmental impact. Enzymatic synthesis, utilizing immobilized lipases such as Candida antarctica lipase B (CALB), offers a greener alternative, operating under milder conditions and often yielding higher product selectivity with fewer by-products. For manufacturers looking to buy this chemical, understanding these synthesis routes can inform quality assessments and supplier selection.
From a chemical properties perspective, Bis(2-ethylhexyl) Sebacate is characterized by its liquid state at room temperature, its pale yellow to colorless appearance, and its mild odor. It is notably insoluble in water but readily soluble in various organic solvents, which dictates its compatibility in different formulations. Its molecular structure, a diester of sebacic acid and branched 2-ethylhexanol, imparts excellent flexibility and stability. Key physical properties include a low melting point of approximately -55°C, a high boiling point, and a density around 0.914 g/mL at 25°C. These attributes make it an ideal plasticizer and lubricant additive, as highlighted by its use in various chemical auxiliary applications.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying chemicals that meet stringent purity and performance standards. Our expertise in chemical synthesis and sourcing ensures that clients receive Bis(2-ethylhexyl) Sebacate of the highest quality. Whether for polymer modification, cosmetic formulation, or industrial lubrication, understanding the synthesis and properties of DOS is key to harnessing its full potential. Partnering with a reliable manufacturer in China like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to this vital chemical intermediate.
Perspectives & Insights
Future Origin 2025
“Enzymatic synthesis, utilizing immobilized lipases such as Candida antarctica lipase B (CALB), offers a greener alternative, operating under milder conditions and often yielding higher product selectivity with fewer by-products.”
Core Analyst 01
“For manufacturers looking to buy this chemical, understanding these synthesis routes can inform quality assessments and supplier selection.”
Silicon Seeker One
“From a chemical properties perspective, Bis(2-ethylhexyl) Sebacate is characterized by its liquid state at room temperature, its pale yellow to colorless appearance, and its mild odor.”