Ningbo Inno Pharmchem Co., Ltd. is dedicated to advancing the understanding and application of essential cosmetic ingredients. Among these, Diazolidinyl Urea stands out as a critical component, widely recognized for its potent preservative properties. This article delves into the scientific underpinnings of Diazolidinyl Urea, exploring its chemical nature, how it functions as a preservative, and its significance in ensuring product safety and longevity within the vast cosmetic industry.

Diazolidinyl Urea, identified by its CAS number 78491-02-8, is a complex organic compound belonging to the family of formaldehyde-releasing preservatives. While the term 'formaldehyde-releasing' might raise concerns, it's important to understand the mechanism and regulatory context. Diazolidinyl Urea slowly breaks down over time, releasing small, controlled amounts of formaldehyde. This slow release mechanism is precisely what makes it an effective broad-spectrum antimicrobial agent. Formaldehyde, in these minute quantities, is highly effective at inhibiting the growth of bacteria, yeast, and mold, which are common contaminants that can spoil cosmetic products and pose risks to consumers.

The efficacy of Diazolidinyl Urea is well-documented. It demonstrates a broad spectrum of activity, meaning it is effective against a wide variety of microorganisms. This is particularly important in cosmetic formulations, which are often water-based and can serve as a breeding ground for microbial contamination. Its ability to combat both Gram-negative and Gram-positive bacteria, as well as fungi like yeast and molds, makes it a robust choice for formulators. Many cosmetic manufacturers utilize Diazolidinyl Urea as part of a comprehensive preservative system. It is often paired with other preservatives, such as parabens or Iodopropynyl Butylcarbamate (IPBC), to create synergistic effects. This combination can broaden the spectrum of activity and enhance the overall preservation power, ensuring that products remain safe throughout their intended shelf life.

Regarding its application, Diazolidinyl Urea is a versatile ingredient suitable for a wide range of cosmetic products. This includes leave-on products like creams, lotions, and serums, as well as rinse-off products such as shampoos, conditioners, and body washes. It is also found in makeup, bubble baths, and baby wipes. The recommended usage level typically falls between 0.1% to 0.5% in finished cosmetic products. Adding it at temperatures below 50°C is generally advised to maintain its stability and efficacy.

Consumer safety is paramount, and the use of Diazolidinyl Urea is governed by regulatory bodies worldwide. Organizations like the Cosmetic Ingredient Review (CIR) Expert Panel have reviewed the safety of Diazolidinyl Urea and concluded that it is safe for use in cosmetics at concentrations up to 0.5%, provided that the levels of free formaldehyde released are within acceptable limits. The slow release mechanism ensures that the concentration of free formaldehyde remains low, minimizing the risk of skin irritation or allergic reactions for most individuals. For consumers concerned about formaldehyde or preservatives in general, understanding the role and safety of ingredients like Diazolidinyl Urea is key. By providing high-quality ingredients and transparent information, Ningbo Inno Pharmchem Co., Ltd. aims to support the development of safe and effective cosmetic products for consumers globally.