NINGBO INNO PHARMCHEM CO.,LTD. is pleased to present an in-depth look at Gamma-Cyclodextrin (CAS 17465-86-0), a fascinating cyclic oligosaccharide that plays a pivotal role in various industries, particularly pharmaceuticals and food science. Understanding its unique properties is key to unlocking its full potential for innovative product development.

Gamma-Cyclodextrin is structurally characterized as a cyclic molecule composed of eight D-glucose units linked by α-1,4 glycosidic bonds. This arrangement creates a toroidal structure with a hydrophilic exterior and a hydrophobic interior cavity. Crucially, its cavity is larger than that of its alpha and beta counterparts, allowing it to encapsulate larger guest molecules. This size advantage is a significant factor in its wide-ranging gamma cyclodextrin applications.

The production of Gamma-Cyclodextrin primarily involves enzymatic processes, typically utilizing cyclodextrin glycosyltransferases (CGTases) acting on starch. While most wild-type CGTases produce a mixture of cyclodextrins, advancements in enzyme engineering and process optimization are leading to more efficient and selective production of gamma-cyclodextrin. NINGBO INNO PHARMCHEM CO.,LTD. is committed to leveraging these advancements to supply high-quality gamma-cyclodextrin.

One of the most significant benefits of Gamma-Cyclodextrin is its role as a solubility enhancer. Many active pharmaceutical ingredients (APIs) and flavor compounds are hydrophobic, limiting their solubility in aqueous systems and thus their bioavailability or effectiveness. By forming inclusion complexes, Gamma-Cyclodextrin effectively shields these hydrophobic molecules within its cavity, dramatically increasing their apparent solubility in water. This makes it an invaluable tool for pharmaceutical formulation and for improving the delivery of nutraceuticals.

Beyond solubility, Gamma-Cyclodextrin also acts as a stabilizer. It can protect sensitive compounds, such as volatile flavors, fragrances, and certain APIs, from degradation caused by light, oxygen, or heat. This protective encapsulation preserves the integrity and efficacy of the encapsulated substance, extending shelf life and maintaining product quality. This is particularly important in the food industry for preserving delicate aromas and in pharmaceuticals for maintaining the stability of APIs.

The applications of Gamma-Cyclodextrin are diverse. In the pharmaceutical sector, it is used to improve the oral bioavailability of drugs, mask unpleasant tastes, and enable controlled or sustained release formulations. Its use as a stabilizer in pharmaceutical excipients is well-documented. In the food industry, it serves as a carrier for flavors and colors, enhancing their stability and release characteristics. It is also employed in cosmetics for encapsulating fragrances and active ingredients. The scientific literature extensively covers its use in drug delivery systems, highlighting its biocompatibility and effectiveness.

For those seeking to buy Gamma-Cyclodextrin, partnering with a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to a product that meets stringent quality standards. We are dedicated to supporting your research and development needs with consistent supply and technical expertise, making us a trusted gamma cyclodextrin supplier for your innovative projects.

In summary, Gamma-Cyclodextrin is more than just a chemical compound; it is an enabling technology. Its unique structural and functional properties make it an indispensable ingredient for companies looking to enhance product performance, stability, and delivery across a multitude of applications. As research continues to uncover new uses, the importance of this versatile cyclodextrin is set to grow.