At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing ingredients that support overall animal health, including cardiovascular well-being. Squalene, a natural triterpene, has demonstrated significant benefits for cardiovascular systems in animals, primarily through its lipid-modulating and antioxidant effects. This article explores the scientific evidence behind these beneficial impacts.

Cardiovascular health in livestock is crucial for productivity and longevity. Factors such as diet, stress, and genetics can influence lipid metabolism and lead to conditions that impair heart function. Squalene plays a multifaceted role in supporting cardiovascular health. It is known to regulate lipid profiles by reducing levels of low-density lipoproteins (LDL), often referred to as 'bad cholesterol', and increasing high-density lipoproteins (HDL), the 'good cholesterol'. This improvement in lipid balance helps prevent the build-up of plaque in arteries, a key factor in atherosclerosis.

The antioxidant properties of squalene are central to its cardioprotective effects. Oxidative stress, particularly the oxidation of LDL, is a significant contributor to cardiovascular disease. Squalene effectively scavenges free radicals and prevents lipid peroxidation, thereby protecting the vascular endothelium and cardiac cells from damage. Studies have shown that squalene can increase the activity of antioxidant enzymes in the heart tissue, such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), further bolstering the heart's defense against oxidative injury.

Moreover, squalene has been observed to inhibit key enzymes involved in cholesterol synthesis, such as HMG-CoA reductase, through a negative feedback mechanism, similar to the action of statin drugs. This enzymatic regulation helps control cholesterol levels within the body, contributing to a healthier cardiovascular environment. By promoting smoother cardiovascular epithelium and clearing inflammatory sites, squalene helps maintain optimal circulatory function.

NINGBO INNO PHARMCHEM CO.,LTD. supplies high-purity squalene, an ingredient that can be incorporated into animal feed formulations to support cardiovascular health. By understanding and utilizing the science behind squalene's mechanisms, animal producers can proactively manage the well-being of their livestock. Our commitment to quality ensures that you receive a reliable source of squalene to enhance animal health outcomes.