NINGBO INNO PHARMCHEM CO.,LTD. provides a closer look at the fundamental aspects of Vitamin E Nicotinate (CAS 16676-75-8), focusing on its chemical properties and the intricacies of its synthesis. Understanding these elements is crucial for appreciating its applications and for manufacturers sourcing this vital compound.

Vitamin E Nicotinate, chemically known as Tocopheryl Nicotinate, is an ester formed through the reaction of Vitamin E (specifically alpha-tocopherol) and nicotinic acid. Its molecular formula is C35H53NO3, with a molecular weight of approximately 535.8 g/mol. The compound typically appears as a yellowish ceraceous solid. Its unique structure, incorporating both the tocopherol and nicotinate moieties, grants it the dual benefits of antioxidant activity and improved microcirculation.

The synthesis of Vitamin E Nicotinate can be achieved through several methods. Industrially, a common approach involves the esterification of alpha-tocopherol with nicotinoyl chloride. This process requires careful control of reaction conditions and the use of acid scavengers. Another method utilizes triphosgene, which acts as a milder chlorinating agent for nicotinic acid, facilitating a one-pot synthesis with good yields and selectivity. For those interested in acquiring this chemical, understanding these Vitamin E Nicotinate synthesis pathways helps in evaluating supplier quality and production capabilities.

Comparative studies of different synthetic routes highlight the triphosgene-mediated synthesis as a favorable method due to its operational safety and efficiency. The resulting Vitamin E Nicotinate from these processes typically exhibits high purity, often exceeding 97.0% assay. Manufacturers looking to source this ingredient will find that NINGBO INNO PHARMCHEM CO.,LTD. adheres to stringent quality control measures to ensure product integrity.

The chemical properties and synthesis insights into Vitamin E Nicotinate underscore its importance as a functional ingredient. For companies looking to purchase Vitamin E Nicotinate for their product lines, partnering with reputable suppliers who employ robust synthesis and quality control methods is paramount. This ensures the efficacy and safety of the final consumer products.