At NINGBO INNO PHARMCHEM CO.,LTD., we believe in transparency and knowledge sharing regarding the chemicals we supply. This article delves into the chemical synthesis and key properties of Dodecylguanidine Hydrochloride (DGH), a compound with significant industrial utility.

The synthesis of Dodecylguanidine Hydrochloride typically involves reacting a dodecylamine derivative with a guanidine source. One common method includes the reaction of dodecylamine with cyanamide or dicyandiamide under controlled conditions, followed by treatment with hydrochloric acid to form the salt. Another pathway might involve the reaction of dodecyl isothiocyanate with guanidine salts. These processes require careful control of reaction parameters such as temperature, pH, and reactant ratios to ensure high purity and yield of the final DGH product. The exact synthetic route can influence the physical form and specific properties of the resulting DGH, highlighting the importance of a well-controlled manufacturing process.

Chemically, Dodecylguanidine Hydrochloride is characterized by its cationic nature, owing to the protonated guanidine group, and the lipophilic dodecyl chain. This amphiphilic nature makes it an excellent surfactant, capable of lowering surface tension and interacting at interfaces. Its antimicrobial activity is attributed to its ability to intercalate into and disrupt the lipid bilayers of microbial cell membranes. DGH is generally soluble in water and polar organic solvents, and it exhibits stability over a broad pH range, making it amenable to various formulation types.

Understanding these synthetic pathways and chemical properties is essential for formulators and researchers utilizing Dodecylguanidine Hydrochloride. NINGBO INNO PHARMCHEM CO.,LTD. is committed to producing DGH of exceptional quality, backed by rigorous quality control measures. We are ready to support your projects by providing reliable Dodecylguanidine Hydrochloride, along with comprehensive technical data and support.