News Articles Tagged: AKT
In Silico Insights: Targeting AKT and BRAF with 2,2'-Bipyridine Derivatives
Explore the computational approach of using molecular docking to understand how 2,2'-Bipyridine derivatives interact with key cancer targets like AKT and BRAF.
Unlocking Anticancer Potential: 2,2'-Bipyridine Derivatives and HepG2 Cells
Explore the emerging research on 2,2'-Bipyridine derivatives as potential anticancer agents, focusing on their impact on HepG2 liver cancer cells and the underlying mechanisms.
The PI3K Pathway and Urolithin B: A Synergistic Approach to Health
Explore the connection between Urolithin B and the PI3K pathway in promoting cellular survival and health.
Anticancer Potential of 2,2'-Bipyridine Derivatives: Targeting HepG2 Cells
An in-depth look at how 2,2'-bipyridine derivatives are being investigated for their anticancer efficacy against hepatocellular carcinoma (HepG2) cells, focusing on apoptosis and ROS mechanisms.
Myricetin and the EGFR-AKT/STAT Pathway: A New Frontier in Combating Neuroinflammation
Delve into the molecular mechanisms of myricetin's anti-inflammatory action, focusing on its interaction with the EGFR-AKT/STAT pathway and its implications for treating neuroinflammatory conditions.
Shikimic Acid: A Natural Approach to Combatting Neurological Inflammation
Examine Shikimic Acid's anti-inflammatory and neuroprotective actions, focusing on its impact on the AKT/Nrf2 and NF-κB pathways for potential use in neurological disease management.
The Science Behind Shikimic Acid's Neuroprotective Effects
Discover how Shikimic Acid's anti-inflammatory actions, driven by its influence on the AKT/Nrf2 and NF-κB pathways, contribute to neuroprotection and offer potential for treating neurological conditions.
Shikimic Acid: Targeting Neuroinflammation Through Pathway Modulation
Investigate how Shikimic Acid's influence on the AKT/Nrf2 and NF-κB pathways provides potent anti-inflammatory and neuroprotective effects, vital for conditions like Parkinson's.
Shikimic Acid: A Promising Compound for Neurological Health
Learn about Shikimic Acid's potent anti-inflammatory and neuroprotective properties, focusing on its impact on the AKT/Nrf2 and NF-κB pathways for potential applications in neurodegenerative diseases.
Understanding Shikimic Acid's Role in Combating Neuroinflammation
Delve into the scientific mechanisms by which Shikimic Acid alleviates neuroinflammation, focusing on its influence on the AKT/Nrf2 and NF-κB pathways. Learn how this compound offers neuroprotective benefits.
Shikimic Acid: A Natural Ally Against Neuroinflammation
Explore how Shikimic Acid's unique properties, particularly its activation of the AKT/Nrf2 pathway and inhibition of NF-κB, offer promising neuroprotection and anti-inflammatory benefits. Discover its potential in combating neurodegenerative diseases.
The Role of (Z)-Guggulsterone in Cancer Therapy: Mechanisms and Research Strategies
Explore how (Z)-Guggulsterone targets cancer cells through apoptosis induction, pathway modulation, and potential therapeutic strategies.
The Role of PUMA in Ipatasertib's Anticancer Mechanism
Deep dive into the function of PUMA, a pro-apoptotic protein, and its indispensable role in mediating the anticancer effects of Ipatasertib.
Ipatasertib: A Precision Medicine Approach to Cancer Treatment
Explore how Ipatasertib aligns with precision medicine principles, targeting specific molecular alterations in cancer and potentially utilizing biomarkers for patient selection.
Ipatasertib in Vivo: Demonstrating Antitumor Activity in Preclinical Models
Examine the in vivo efficacy of Ipatasertib in preclinical cancer models, highlighting its antitumor effects and the critical role of PUMA.
The PI3K/Akt Pathway: A Key Target in Cancer Therapy with Ipatasertib
Explore the critical role of the PI3K/Akt pathway in cancer and how Ipatasertib, a selective pan-Akt inhibitor, targets this pathway for therapeutic benefit.
Beyond Apoptosis: Chrysin's Role in Modulating Cancer Cell Survival and Metastasis
This article examines how Chrysin influences cancer cell survival pathways and inhibits metastasis, offering a multi-pronged approach to cancer treatment.
The Molecular Maestro: Understanding Urolithin B's Impact on Cellular Signaling Pathways
Delve into the molecular mechanisms of Urolithin B, exploring its effects on key cellular signaling pathways like PI3K/Akt and JNK, and how these impact neuron survival and brain health.