News Articles Tagged: LAT1

Advancing Precision Medicine: The Role of LAT1 in Targeted Therapies

Explore how understanding the LAT1 transporter is enabling the development of precision medicine approaches, particularly in oncology and beyond.

The Molecular Dance: Understanding LAT1 Inhibition Mechanisms

A deep dive into the biochemical intricacies of LAT1 inhibition, explaining how compounds like JPH203 and BCH interact with the transporter at a molecular level.

Beyond Cancer: Exploring LAT1 Inhibitors for Neurological Conditions

Investigate the emerging research on LAT1 inhibitors, including JPH034, and their potential applications in treating neurological disorders like Multiple Sclerosis.

JPH203: A Breakthrough LAT1 Inhibitor for Biliary Tract Cancer Treatment

Delve into the promising clinical development of JPH203 (Nanvuranlat) as a novel therapeutic agent for biliary tract cancer, highlighting its targeted approach and potential impact.

The Cryo-EM Revolution: Unraveling the Secrets of the LAT1 Transporter

Discover how cutting-edge cryo-electron microscopy (cryo-EM) is providing never-before-seen structural details of the LAT1 transporter, paving the way for novel drug design.

Understanding the Role of LAT1 in Cancer: Insights from JPH203 Research

Explore how the L-type amino acid transporter 1 (LAT1) is implicated in cancer progression and how JPH203, a selective LAT1 inhibitor, is emerging as a promising therapeutic agent.