News Articles Tagged: p53

The Role of p53 and GRASP65 in Dihydromyricetin-Mediated Anti-Cancer Effects

Delve into the molecular pathways of dihydromyricetin's anti-cancer action, focusing on p53 activation and GRASP65 downregulation. Insights from NINGBO INNO PHARMCHEM CO.,LTD. on DHM's precise targeting.

Dihydromyricetin in Ovarian Cancer: Targeting Apoptosis and Overcoming Chemoresistance

Ningbo Innopharmchem presents research on dihydromyricetin's role in ovarian cancer, focusing on apoptosis induction, p53 activation, and reversal of chemoresistance through survivin downregulation. Buy DHM for research.

Understanding Cellular Senescence: The Science Behind FOXO4-DRI and p53

Delve into the intricacies of cellular senescence and the role of the FOXO4-DRI and p53 interaction. Learn how this peptide can be a key to combating age-related decline.

The P53-P21 Axis: A Critical Pathway in Cellular Defense Against DNA Damage

Explore the vital P53-P21 axis, detailing how p53 activation influences P21 expression to control the cell cycle and facilitate DNA repair, acting as a crucial cellular defense mechanism.

The P21 Peptide: A Key Player in Cell Cycle Control and Its Implications for Cancer Therapy

Discover how the P21 peptide regulates the cell cycle and its role in understanding disease development, offering insights into potential therapeutic strategies for cancer.

Understanding P21: The Guardian of the Cell Cycle and Its Link to Cancer Prevention

Explore the critical role of the P21 peptide in cell cycle regulation, its connection to the P53 pathway, and how its gene polymorphism influences disease susceptibility, particularly in cancer prevention.

Synthetic Peptides in Oncology: The Case of PNC-27 and its Impact on Cancer Cell Membranes

Explore the cutting edge of oncology with synthetic peptides like PNC-27, focusing on its mechanism of action which involves targeting cancer cell membranes and inducing necrosis independently of p53.

The Role of PNC-27 in Targeting Cancer: A P53-Independent Strategy

Examine how PNC-27's innovative strategy bypasses the p53 pathway to eliminate cancer cells by targeting HDM-2, offering a novel therapeutic avenue for various cancers including leukemia.

PNC-27: Harnessing HDM-2 Interaction for Targeted Cancer Cell Necrosis

Examine the scientific basis of PNC-27's anticancer activity, focusing on its interaction with HDM-2 to induce p53-independent necrosis in cancer cells, applicable to various tumor types including leukemia.

The Science Behind PNC-27: A Novel Approach to Targeting Cancer

Delve into the scientific details of PNC-27, an anti-cancer peptide that selectively induces necrosis in tumor cells by interacting with HDM-2, offering a p53-independent therapeutic strategy.

Cardiogen Peptide and Apoptosis Inhibition: A New Hope for Cellular Preservation

Explore how Cardiogen peptide's ability to inhibit apoptosis, potentially through p53 protein regulation, offers new avenues for cellular preservation and disease treatment.