DABCYL-OSU: Precision Labeling for Advanced Research
Enhance your biochemical studies with a highly effective succinimidyl ester for protein and peptide modification.
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![4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester](https://www.nbinno.com/2025/webimg/gemini_688de3d401983_1754129364.png)
4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester
This compound is a vital reagent for researchers requiring accurate and efficient labeling of proteins and peptides. Its succinimidyl ester group readily reacts with amine functionalities, enabling the formation of stable peptide bonds. This characteristic makes it invaluable for various biochemical assays and biotechnological applications.
- Leverage this reagent for precise peptide modification, ensuring high fidelity in your synthesis workflows.
- Utilize its capabilities for effective protein labeling through amino groups, a critical step in many biological assays.
- Explore its role as an ideal long wavelength quencher, enhancing the signal-to-noise ratio in your experiments.
- Integrate its function as an acceptor chromophore in FRET studies to unravel complex molecular interactions.
Key Advantages
Versatile Amine Reactivity
The succinimidyl ester moiety ensures strong and specific reactions with primary amines, facilitating robust conjugation for protein labeling.
FRET Study Applications
Its properties as an acceptor chromophore make it exceptionally useful for Förster Resonance Energy Transfer (FRET) studies, enabling detailed insights into molecular dynamics. It is ideal for FRET assay development.
Automated Synthesis Compatible
The compound's suitability for N-terminal modification in automated peptide synthesis streamlines complex laboratory procedures.
Key Applications
Protein Labeling
Facilitates the covalent attachment of fluorescent dyes or other labels to proteins via amine groups, crucial for fluorescent probes in biochemistry.
Peptide Synthesis
Enables precise N-terminal modification of peptides, vital for developing custom peptide sequences in research and development.
Bioconjugation
Acts as an efficient bioconjugation reagent, linking biomolecules for various diagnostic and therapeutic applications.
FRET Analysis
Serves as a key component in FRET systems, providing a non-fluorescent acceptor for studying molecular interactions and conformational changes.