1,3-Di(1H-imidazol-1-yl)propane: A Versatile Building Block for MOFs and Coordination Chemistry
Discover the essential properties and wide-ranging applications of this key chemical intermediate.
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1,3-Di(1H-imidazol-1-yl)propane
This compound serves as a critical component in the construction of Metal-Organic Frameworks (MOFs) and coordination polymers. Its flexible nature and the presence of imidazole rings make it an excellent choice for creating intricate and functional structures. Research into its antifungal imidazole derivatives highlights its potential in developing new antimicrobial agents.
- Explore its use as a MOF ligand in advanced materials synthesis, contributing to novel porous structures with tailored properties.
- Investigate its role in coordination chemistry, where it acts as a bridging ligand to form complexes with diverse metal ions.
- Discover its potential in catalysis and materials science, leveraging its unique structural and chemical characteristics.
- Learn about the ongoing research into its antimicrobial imidazole compounds, showcasing its potential in medicinal chemistry and drug discovery.
Key Advantages of 1,3-Di(1H-imidazol-1-yl)propane
Structural Flexibility
The propane spacer provides significant conformational flexibility, allowing this flexible ligand for MOFs to adapt to various metal geometries and co-ligands, crucial for designing diverse framework architectures.
Versatile Coordination
With two imidazole nitrogen atoms, it effectively bridges metal centers, enabling the formation of extended 1D, 2D, and 3D coordination polymers, demonstrating its utility as a key bis(imidazole) ligand application.
Potential Biological Activity
Studies indicate potential antimicrobial and antifungal properties, making it an interesting subject for research in developing new therapeutic agents, aligning with interests in imidazole-based organic synthesis.
Key Applications
MOF Synthesis
As a critical MOF ligand, it is integral to constructing novel porous materials for applications in gas storage, separation, and catalysis.
Coordination Chemistry
Its ability to form stable complexes with various metal ions makes it invaluable in advanced coordination chemistry building blocks, facilitating the study of new material properties.
Catalysis
The unique coordination environment it creates with metal centers can lead to highly effective catalysts for various chemical transformations.
Drug Discovery
Research into its antifungal imidazole derivatives and other potential biological activities positions it as a compound of interest in pharmaceutical research and development.
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