High-Purity 2'-(Dicyclohexylphosphino)-N,N-dimethyl[1,1'-biphenyl]-4-amine: A Versatile Ligand for Advanced Organic Synthesis
Unlock groundbreaking chemical transformations with our premium phosphine ligand for superior catalytic performance.
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2'-(Dicyclohexylphosphino)-N,N-dimethyl[1,1'-biphenyl]-4-amine
This high-purity organic synthesis intermediate serves as a crucial phosphine ligand in palladium-catalyzed cross-coupling reactions. Its unique structure enhances efficiency in reactions like Suzuki-Miyaura coupling and Buchwald-Hartwig amination, making it indispensable for synthesizing complex molecules relevant to pharmaceuticals and fine chemicals. Its potential in medicinal chemistry for modulating inflammatory pathways and cell signaling further underscores its versatility.
- Leverage the power of palladium-catalyzed cross-coupling reactions with this essential organic synthesis intermediate.
- Achieve high yields in Buchwald-Hartwig amination, a key process for forming C-N bonds.
- Explore innovative medicinal chemistry applications, including potential anti-inflammatory therapies and cell signaling modulation.
- Benefit from high purity standards (≥98%) ensuring reliable catalytic performance.
Advantages Offered
Enhanced Catalytic Efficiency
The specific electronic and steric properties of this phosphine ligand significantly boost the performance of palladium catalysts, enabling faster reaction times and higher turnover numbers, critical for efficient organic synthesis intermediate production.
Broad Reaction Scope
Its efficacy in both Suzuki-Miyaura coupling for C-C bond formation and Buchwald-Hartwig amination for C-N bond formation makes it a highly versatile tool for chemists working on diverse synthetic targets.
Medicinal Chemistry Potential
Beyond catalysis, the compound's interaction with biological pathways, such as inhibiting 5-lipoxygenase, opens avenues for its use in developing new therapeutic agents, highlighting its broader impact.
Key Applications
Catalysis
As a vital phosphine ligand, it optimizes palladium-catalyzed reactions like Suzuki-Miyaura coupling and Buchwald-Hartwig amination, crucial for forming complex molecular structures.
Pharmaceutical Synthesis
An essential intermediate in the large-scale synthesis of active pharmaceutical ingredients (APIs) and drug candidates, ensuring purity and yield.
Fine Chemical Production
Used in the manufacturing of specialized organic compounds for various industrial applications, requiring high specificity and consistent quality.
Medicinal Research
Investigated for its biological activities, including potential roles in anti-inflammatory therapies and modulation of cell signaling pathways.