(2S,5S)-Hexane-2,5-diol: A Versatile Chiral Building Block
Unlock advanced chemical synthesis with a precisely structured chiral diol, ideal for catalysis and specialized materials.
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(2S,5S)-Hexane-2,5-diol
This C2-symmetric chiral diol is a cornerstone for creating enantiomerically pure compounds, vital for pharmaceuticals and advanced materials. Its well-defined stereochemistry and reactive hydroxyl groups make it an indispensable component in modern chemical manufacturing and research.
- Leverage its role as a reagent for asymmetric syntheses to achieve high stereochemical purity in your target molecules.
- Utilize this compound as a precursor for the synthesis of new phospholanes, crucial for material science innovations.
- Incorporate its structure in the synthesis of chiral ligands for asymmetric catalysis, enabling precise control over reaction outcomes.
- Explore its application in the pharmaceutical industry as a key chiral building block for drug development.
Key Advantages
High Stereochemical Purity
Achieve exceptional enantiomeric and diastereomeric excess, critical for demanding applications in chiral chemistry and pharmaceutical synthesis, facilitating reliable asymmetric syntheses.
Versatile Chemical Reactivity
The two hydroxyl groups offer reactive sites for a broad range of chemical transformations, enabling its use as a monomer in polymer production and a precursor for various functional molecules.
Efficient Biocatalytic Synthesis
Benefit from advanced biocatalytic production methods that provide high yields and excellent stereoselectivity, making the synthesis of this chiral building block more sustainable and productive.
Key Applications
Asymmetric Catalysis
Serves as a precursor for chiral ligands, such as diphosphites, used in metal-catalyzed reactions like rhodium-catalyzed asymmetric hydroformylation, influencing enantioselectivity.
Pharmaceutical Synthesis
Acts as a crucial chiral building block for creating enantiomerically pure intermediates and active pharmaceutical ingredients, essential for drug efficacy and safety.
Specialty Polymers
Incorporated as a monomer in the synthesis of specialty polymers, contributing to unique material properties like flexibility and thermal resistance in polyesters and polyurethanes.
Organic Synthesis
A valuable reagent in organic synthesis for creating new phospholanes and other complex chiral molecules, advancing research in material science and chemical development.