4-Amino-2-chloro-6-(trifluoromethyl)pyridine: A Key Intermediate
Discover the synthesis, properties, and diverse applications of this vital building block in chemical innovation.
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4-Amino-2-chloro-6-(trifluoromethyl)pyridine
This compound is a crucial building block in organic synthesis, valued for its unique structural features that enable the creation of complex molecules. Its pyridine core, functionalized with both a chlorine atom and a trifluoromethyl group, imparts specific electronic and reactive properties essential for pharmaceutical and agrochemical development.
- Explore the key applications of trifluoromethyl pyridine derivatives in modern chemistry.
- Understand the synthesis of 4-Amino-2-chloro-6-(trifluoromethyl)pyridine through advanced chemical methodologies.
- Investigate the significant role of the trifluoromethyl group in medicinal chemistry for enhanced drug properties.
- Learn about the properties of 4-Amino-2-chloro-6-(trifluoromethyl)pyridine, including its physical and chemical characteristics.
Key Advantages
Synthetic Versatility
Leverage its structure for diverse chemical transformations, making it invaluable for complex organic synthesis and CAS 34486-22-1 applications.
Enhanced Bioactivity
The presence of the trifluoromethyl group can significantly boost the lipophilicity and metabolic stability of resulting compounds, contributing to potent anticancer activity trifluoromethylpyridine derivatives.
Efficient Production Routes
Benefit from established cyclocondensation synthesis trifluoromethylpyridines and palladium-catalyzed amination pyridine methods for reliable and scalable production.
Key Applications
Pharmaceutical Intermediates
A critical component in the synthesis of various drug candidates, particularly those targeting cancer and infectious diseases, showcasing its role in medicinal chemistry building blocks.
Agrochemical Development
Used in the creation of pesticides and herbicides, contributing to crop protection and agricultural efficiency, highlighting its importance in agrochemical intermediate development.
Material Science
Its unique electronic properties make it a candidate for novel material synthesis, fitting within the scope of fluorinated heterocyclic synthesis research.
Research and Development
An essential reagent for academic and industrial researchers exploring new synthetic pathways and the antimicrobial properties pyridine derivatives.