5-(Trifluoromethyl)isatin: A Key Chemical Intermediate for Advanced Synthesis
Explore the properties, applications, and synthetic utility of 5-(Trifluoromethyl)isatin (CAS 345-32-4) for your research and development needs.
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5-(Trifluoromethyl)isatin
5-(Trifluoromethyl)isatin, identified by CAS number 345-32-4, is a crucial chemical intermediate valued for its unique structural features and reactivity. Its molecular formula is C9H4F3NO2 with a molecular weight of 215.13. The presence of a trifluoromethyl group at the 5-position significantly enhances its lipophilicity and metabolic stability, making it a sought-after building block in various advanced synthesis projects. This compound is essential for developing novel pharmaceuticals and agrochemicals.
- Discover the benefits of using 5-(Trifluoromethyl)isatin in organic synthesis, leveraging its unique properties for complex molecular construction.
- Explore how the trifluoromethyl group in 5-(Trifluoromethyl)isatin enhances lipophilicity and metabolic stability, crucial for pharmaceutical applications.
- Understand the reactivity of 5-(Trifluoromethyl)isatin in nucleophilic substitutions and cycloadditions, vital for creating novel chemical entities.
- Learn about the potential of 5-(Trifluoromethyl)isatin as a key building block in medicinal chemistry for the development of new therapeutic agents.
Key Advantages
Enhanced Reactivity
The electronegativity of the fluorine atoms in the trifluoromethyl group of 5-(Trifluoromethyl)isatin contributes to its distinct electronic properties, influencing its reactivity in various chemical transformations, which is a significant advantage for synthetic chemists.
Versatile Building Block
As a 5-(Trifluoromethyl)isatin synthesis intermediate, this compound serves as a versatile building block, enabling the efficient construction of complex organic molecules required for cutting-edge research and product development.
Pharmaceutical Potential
The application of 5-(Trifluoromethyl)isatin in medicinal chemistry is well-documented, offering a valuable starting point for the synthesis of drug candidates with improved pharmacological profiles.
Key Applications
Pharmaceutical Intermediates
Leverage 5-(Trifluoromethyl)isatin as a critical component in the synthesis of Active Pharmaceutical Ingredients (APIs), contributing to the development of novel therapeutics.
Agrochemical Development
Utilize the unique properties of 5-(Trifluoromethyl)isatin to engineer advanced agrochemicals with enhanced efficacy and stability.
Organic Synthesis
Employ 5-(Trifluoromethyl)isatin as a versatile reagent in various organic synthesis pathways, facilitating the creation of intricate molecular structures.
Medicinal Chemistry Research
Investigate the biological activities of compounds derived from 5-(Trifluoromethyl)isatin, exploring new avenues in drug discovery and design.