DEPBT: The Superior Coupling Reagent for Efficient Peptide Synthesis and Reduced Racemization
Discover the revolutionary DEPBT for unmatched peptide synthesis efficiency and minimal racemization.
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3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one
DEPBT is a cutting-edge peptide coupling reagent that significantly enhances efficiency and minimizes critical side reactions in peptide synthesis. Its unique chemical structure provides a remarkable resistance to racemization, making it an invaluable tool for creating complex and high-purity peptides. Unlike many traditional reagents, DEPBT offers superior performance, even with challenging amino acid derivatives that are prone to epimerization.
- Experience exceptional peptide synthesis with DEPBT, a leading peptide coupling reagent known for its robust performance.
- Achieve high yields and fast kinetics in your amide bond formation processes, leveraging DEPBT's advanced chemical properties.
- Overcome the challenges of coupling prone amino acids, ensuring the stereochemical integrity of your synthesized peptides.
- Benefit from the stability and ease of handling offered by DEPBT, a crystalline phosphate that simplifies your laboratory workflow.
Advantages of Using DEPBT
Minimized Racemization
DEPBT is specifically designed to offer remarkable resistance to racemization, a crucial factor in maintaining the stereochemical purity of peptides, thus improving the quality of your research and products.
Enhanced Coupling Efficiency
The reagent facilitates efficient peptide bond formation, leading to higher yields and faster reaction times, which is essential for both solution-phase and solid-phase peptide synthesis.
Broad Applicability
DEPBT proves effective even with amino acid derivatives that are notoriously difficult to couple, including those with unprotected hydroxyl or imidazole groups, simplifying synthetic strategies.
Key Applications
Peptide Synthesis
Utilize DEPBT for precise and efficient peptide synthesis, from simple linear peptides to complex cyclic and sterically hindered sequences, ensuring high purity and configuration retention.
Amide Bond Formation
DEPBT is an excellent choice for general amide bond formation in organic synthesis, providing a reliable method for joining carboxylic acids and amines with minimal epimerization.
Pharmaceutical Research
In pharmaceutical research, DEPBT aids in the development of new drug candidates by enabling the efficient synthesis of peptide-based therapeutics with improved stereochemical control.
Complex Natural Products Synthesis
The reagent's efficacy extends to the synthesis of intricate natural products, where precise control over stereochemistry is paramount for achieving the target molecular structure.