Diethyl Maleate: Synthesis, Properties, Applications, and Safety
Explore the multifaceted uses of Diethyl Maleate (CAS 141-05-9), a vital organic compound in synthesis and industry.
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Diethyl Maleate
Diethyl Maleate, identified by CAS number 141-05-9, is a pivotal organic compound recognized for its utility as a dienophile in organic synthesis. Its applications extend to being a critical intermediate in the manufacturing of a wide array of products, including plastics, pigments, pharmaceuticals, and agricultural chemicals. Furthermore, it plays a role in the production of coatings, adhesives, and copolymers, highlighting its versatility in various industrial sectors.
- The use of Diethyl Maleate in organic synthesis as a dienophile is crucial for many chemical transformations.
- As a key intermediate for plastics, its role in polymer production is significant.
- Its applications as an intermediate for pharmaceuticals underscore its importance in the healthcare industry.
- The compound's ability to deplete glutathione is a notable biochemical property with implications in cellular research.
Key Advantages of Diethyl Maleate
Versatile Synthetic Utility
Diethyl Maleate serves as a valuable dienophile in Diels-Alder type cycloaddition reactions, enabling complex organic synthesis pathways for a variety of target molecules. This makes it indispensable for organic synthesis.
Broad Industrial Intermediate Role
Its function as an intermediate for plastics, pigments, pharmaceuticals, and agricultural products showcases its broad utility across multiple industries, contributing to the creation of essential goods.
Biochemical Research Tool
With its ability to deplete glutathione, Diethyl Maleate is employed in biochemical research to study cellular pathways, oxidative stress, and the function of thiol groups in biological systems, acting as a key glutathione depleting agent.
Key Applications
Organic Synthesis
As a crucial dienophile, Diethyl Maleate is instrumental in facilitating Diels-Alder reactions and other synthetic processes, a core aspect of organic synthesis.
Polymer and Plastics Industry
It acts as an essential intermediate for the production of various plastics and polymers, contributing to the material science sector and the development of advanced materials.
Pharmaceutical Manufacturing
Diethyl Maleate is utilized as an intermediate in the synthesis of pharmaceutical compounds, playing a role in the development of medicines and healthcare products.
Agrochemicals and Coatings
Its application extends to the agricultural sector as an intermediate for agrochemicals and in the production of coatings and adhesives, enhancing product performance and durability.