Fmoc-Ala-Wang Resin for Efficient Solid Phase Peptide Synthesis
Unlock advanced peptide synthesis with high-quality Fmoc-Ala-Wang Resin, a cornerstone for researchers and industries.
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Fmoc-Ala-Wang Resin
Fmoc-Ala-Wang Resin is a critical component in Solid Phase Peptide Synthesis (SPPS), offering unparalleled reliability and efficiency. Its structure combines a polystyrene-based core with divinylbenzene cross-linking for stability, and the well-established Wang linker. This combination ensures robust performance throughout the peptide chain elongation process. The resin is pre-loaded with Fmoc-L-Alanine, a common starting point for many peptide sequences, facilitating straightforward synthesis workflows.
- Discover the benefits of using Wang resin for peptide synthesis; it's known for its compatibility with Fmoc chemistry.
- Explore the precise cleavage conditions for Fmoc-Ala-Wang Resin, ensuring peptide integrity.
- Learn why Fmoc amino acid Wang resins are a preferred choice for researchers aiming for high peptide yield and purity.
- Understand the importance of selecting the right peptide synthesis support resins for your specific project needs.
Key Advantages
High Compatibility with Fmoc Chemistry
The Fmoc-Ala-Wang Resin is designed to work seamlessly with the Fmoc strategy, allowing for mild deprotection steps and orthogonality with side-chain protecting groups, crucial for complex peptide synthesis.
Robust and Stable Structure
Featuring a polystyrene-based core cross-linked with divinylbenzene, this resin offers excellent mechanical stability and chemical resistance, vital for enduring multiple synthesis cycles when aiming for high peptide yield.
Mild and Efficient Cleavage
The Wang linker attached to the resin allows for the cleavage of the synthesized peptide under mild acidic conditions (e.g., TFA), minimizing the risk of side-chain modification or degradation and ensuring high purity of the final product.
Key Applications
Peptide Synthesis
Fmoc-Ala-Wang Resin is extensively used in the automated and manual synthesis of peptides, supporting both research and industrial applications for custom peptide synthesis.
Solid Phase Synthesis
As a workhorse in Solid Phase Peptide Synthesis (SPPS), this resin provides a reliable solid support for building peptide chains efficiently, making it a key reagent for solid phase synthesis.
Chemical Synthesis
Beyond peptides, the versatile nature of Wang resin makes it valuable in broader chemical synthesis applications where a functionalized solid support is required, contributing to diverse chemical synthesis projects.
Drug Discovery Research
Researchers in drug discovery utilize this resin to synthesize peptide libraries and potential therapeutic agents, leveraging its consistent performance for building blocks for drug discovery.