High Purity Azido-PEG3-Alcohol for Advanced Chemical Synthesis and Biomedical Applications
A versatile PEG linker enabling click chemistry, PROTAC synthesis, and novel material development.
Get a Quote & SampleProduct Core Value
Azido-PEG3-Alcohol
Azido-PEG3-Alcohol (N3-PEG3-OH), CAS 86520-52-7, is a high-purity polyethylene glycol derivative essential for modern chemical synthesis and biomedical research. This compound features a terminal azide group for efficient click chemistry reactions and a terminal hydroxyl group for further functionalization or conjugation. It is widely used in PROTAC linker synthesis, drug delivery systems, nanotechnology, and the development of new materials, offering enhanced solubility and stability.
- Facilitate PROTAC Linker Synthesis: Explore the utility of Azido-PEG3-Alcohol in constructing complex PROTAC molecules, vital for targeted protein degradation research.
- Enable Click Chemistry Reactions: Utilize the azide functional group for facile and specific conjugation with alkyne-containing molecules, a cornerstone of modern bioconjugation techniques.
- Enhance Drug Delivery Systems: Leverage the PEGylation benefits of Azido-PEG3-Alcohol to improve the solubility, bioavailability, and stability of therapeutic agents.
- Advance Nanomaterial Research: Integrate Azido-PEG3-Alcohol into novel nanomaterials and functional coatings to impart desired properties for various applications.
Key Advantages
Versatile Bifunctionality
The presence of both azide and hydroxyl end groups on the Azido-PEG3-Alcohol molecule provides a powerful platform for diverse chemical modifications and conjugations, supporting complex synthetic strategies.
Improved Biomedical Properties
The polyethylene glycol (PEG) chain in this linker contributes to improved water solubility, reduced immunogenicity, and enhanced stability when incorporated into biomolecules or nanoparticles.
High Purity and Reliability
With a purity of ≥98% (GC), Azido-PEG3-Alcohol ensures reliable and reproducible results in sensitive chemical synthesis and biological applications.
Key Applications
Click Chemistry
Azido-PEG3-Alcohol is a fundamental reagent for click chemistry reactions, enabling the efficient conjugation of biomolecules and materials through stable triazole linkages.
PROTAC Synthesis
As a key component in PROTAC synthesis, this linker facilitates the construction of molecules designed for targeted protein degradation, revolutionizing drug discovery.
Drug Delivery Platforms
Its PEGylation properties make Azido-PEG3-Alcohol ideal for developing advanced drug delivery systems, enhancing therapeutic efficacy and patient compliance.
Nanotechnology and Materials Science
This compound is instrumental in surface modification, nanoparticle synthesis, and the creation of functional coatings, contributing to advancements in nanotechnology and materials science.