TBTU: The Efficient Peptide Coupling Reagent for Advanced Organic Synthesis
Unlock faster, cleaner peptide synthesis with this advanced uronium salt coupling reagent.
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Tetramethyluronium tetrafluoroborate coupling reagent
This potent chemical is a cornerstone for modern peptide synthesis, enabling the efficient formation of peptide bonds with high fidelity. Its structure allows for the activation of carboxylic acids, streamlining the process without the need for pre-activation steps, which is crucial for complex molecular assembly.
- Activate carboxylic acid for peptide synthesis, ensuring robust and reliable bond formation in your research.
- Benefit from fast reaction speed, low by-products, and minimal elimination rates, leading to cleaner reaction profiles.
- Discover the utility of this key component in the synthesis of lorlatinib, a testament to its effectiveness in pharmaceutical development.
- Explore its application as a desulfurization and cyclization agent for synthesizing 1,3,4-oxadiazoles under mild, environmentally friendly conditions.
Advantages it Brings
Streamlined Synthesis
As a highly efficient peptide coupling reagent, it simplifies complex syntheses, making your research more productive.
Enhanced Purity
The low by-product generation and elimination rates directly contribute to higher purity of synthesized peptides, vital for solid phase peptide synthesis.
Versatile Applications
Beyond standard peptide synthesis, its application in creating heterocycles showcases its versatility in organic synthesis.
Key Applications
Peptide Synthesis
Crucial for the precise and efficient construction of peptide chains, supporting breakthroughs in peptide research and development. This reagent is central to solid phase peptide synthesis.
Pharmaceutical Intermediates
Plays a key role in synthesizing complex molecules like lorlatinib, accelerating drug discovery and development pipelines.
Heterocyclic Chemistry
Facilitates the synthesis of valuable 1,3,4-oxadiazoles, important structures in medicinal chemistry and materials science.
General Organic Synthesis
Its broad utility as a coupling reagent makes it an indispensable tool for various challenging transformations in organic synthesis.