Tert-Butyl Cyanoacetate (CAS 1116-98-9): A Versatile Reagent for Organic Synthesis

Explore the chemical properties and diverse applications of this essential fine chemical intermediate.

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Advantages of Using tert-Butyl Cyanoacetate

Synthesis Versatility

The molecule's reactivity makes it a cornerstone for complex tert-butyl cyanoacetate synthesis strategies, enabling the creation of diverse molecular architectures.

Pharmaceutical Relevance

Its crucial role in enhancing beta-selectivity in nucleoside coupling makes it indispensable for researchers developing new pharmaceutical compounds.

Chemical Reactivity

Understanding and utilizing tert-butyl cyanoacetate chemical properties allows chemists to fine-tune reaction conditions for higher yields and purer products.

Key Applications

Organic Synthesis

A key building block in numerous organic reactions, facilitating the formation of complex molecules through controlled chemical transformations, essential for tert-butyl cyanoacetate applications.

Pharmaceutical Intermediates

Serves as a critical intermediate in the production of active pharmaceutical ingredients (APIs), supporting the development of new drugs and therapies.

Vinylogous Urea Production

Directly employed in the synthesis of vinylogous urea, a class of compounds with potential biological activities and applications in materials science.

Nucleoside Chemistry

Acts as an additive to improve stereoselectivity in sugar nucleoside base coupling, a fundamental step in creating novel nucleotides and nucleic acid analogs.