Trimethylsilylacetylene CAS 1066-54-2: A Versatile Building Block for Organic Synthesis and Material Science

Discover the utility of Trimethylsilylacetylene in chemical synthesis and advanced material applications.

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Advantages Provided by the Product

Enhanced Safety and Handling

Unlike gaseous acetylene, Trimethylsilylacetylene is a liquid, simplifying handling and reducing safety risks in laboratory and industrial settings. This makes the trimethylsilylacetylene synthesis of target compounds more accessible.

Versatile Reactivity in Synthesis

Its structure allows for a wide range of reactions, including palladium-catalyzed coupling and nucleophilic attacks, making it an indispensable tool for organic synthesis building blocks.

Material Science Innovation

As a precursor in laser-induced polymerization of ethynyltrimethylsilane, it enables the efficient chemical vapor deposition of polycarbosilane films, contributing to advancements in material science.

Key Applications

Ethynylation Reactions

Trimethylsilylacetylene is a valuable reagent used in ethynylation by palladium(0)-catalyzed coupling/condensation with aryl and vinyl halides and triflates, showcasing its importance in organic synthesis building blocks.

Chemical Vapor Deposition (CVD)

The compound facilitates the efficient chemical vapor deposition of polycarbosilane films through laser-induced polymerization, highlighting its role in laser induced polymerization ethynyltrimethylsilane.

Cross-Coupling Reactions

It acts as a substrate for nickel-catalyzed cross-coupling with benzonitriles, demonstrating its utility in various catalytic processes and advancing trimethylsilylacetylene chemical properties understanding.

Asymmetric Synthesis

Trimethylsilylacetylene is a common intermediate for asymmetric synthesis, enabling the creation of stereochemically defined molecules and reinforcing its status as a silane protected acetylene.