Unlock Advanced Bioconjugation: The Power of 11-Maleimidoundecanoic Acid for Life Sciences
Discover the versatile applications of 11-Maleimidoundecanoic Acid in revolutionizing bioconjugation and chemical synthesis.
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11-Maleimidoundecanoic Acid
11-Maleimidoundecanoic Acid is a dual-functional molecule, featuring both a reactive maleimide group and a versatile carboxylic acid terminus. This unique combination makes it an indispensable tool for creating stable covalent linkages between diverse molecules, enabling advanced applications in life sciences research and development.
- Facilitate protein purification cross linker applications with the reactive maleimide group, which readily forms stable thioether bonds with cysteine residues.
- Enhance peptide synthesis reagent capabilities by providing a stable amide bond formation through its carboxylic acid group, crucial for building complex peptide chains.
- Enable precise PROTAC linker design, leveraging the long alkyl chain for optimal molecular architecture and functionality in targeted protein degradation.
- Explore advanced polymer modification with maleimides, allowing for the introduction of specific functionalities and improved material properties for various industrial and biomedical uses.
Advantages Offered
Versatile Conjugation Capabilities
The distinct maleimide and carboxylic acid moieties allow for selective and robust bioconjugation chemistry, creating stable conjugates for numerous research purposes.
Tailored Molecular Design
The strategic placement of the maleimide and carboxylic acid on an eleven-carbon chain offers significant flexibility in molecular design for applications like PROTAC linker design.
Enhanced Research Applications
As a valuable fluorescent probe and a key component in peptide synthesis, it significantly expands the toolkit available for intricate biological and chemical studies.
Key Applications
Bioconjugation
Utilize the maleimide group for efficient bioconjugation chemistry, forming stable bonds with thiols on proteins and other biomolecules.
Peptide Synthesis
Integrate this compound as a peptide synthesis reagent to introduce unique modifications and functionalities into peptide sequences.
PROTAC Linker Design
Employ its structure as a flexible linker in the development of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
Material Science
Apply it for polymer modification with maleimides, creating novel functional materials with tailored properties for advanced applications.