High-Purity Fmoc-Asn(Trt)-OH: A Key Building Block for Advanced Peptide Synthesis
Unlock the potential of peptide synthesis with our premium Fmoc-Asn(Trt)-OH, ensuring purity and efficiency in every step.
Get a Quote & SampleProduct Core Value
Fmoc-Asn(Trt)-OH
Fmoc-Asn(Trt)-OH is a critical Fmoc-protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). Its unique structure, featuring a trityl protecting group on the asparagine side chain, significantly enhances the purity and yield of synthesized peptides by preventing undesirable side reactions, such as dehydration, which commonly occur during activation with carbodiimide reagents. This derivative exhibits excellent solubility in common peptide synthesis solvents like NMP and DMF, facilitating smoother reactions compared to unprotected asparagine.
- Discover the advantages of Fmoc-Asn(Trt)-OH for peptide synthesis, ensuring cleaner reaction profiles and higher purity end products.
- Understand the efficient Fmoc-Asn(Trt)-OH deprotection process using TFA, crucial for successful peptide chain elongation.
- Learn about the optimal Fmoc-Asn(Trt)-OH solubility in standard peptide synthesis solvents, simplifying reaction setup and execution.
- Explore options to buy Fmoc-Asn(Trt)-OH online from reliable suppliers, guaranteeing high Fmoc-Asn(Trt)-OH purity for your research and production needs.
Key Advantages Offered
Prevents Dehydration Side Reactions
The trityl group on Fmoc-Asn(Trt)-OH effectively blocks the amide side chain, critically preventing dehydration reactions during peptide coupling, a common issue with unprotected asparagine.
Enhanced Solubility for Smooth Synthesis
Achieve better reaction kinetics and easier handling due to the superior solubility of Fmoc-Asn(Trt)-OH in commonly used organic solvents, facilitating the Fmoc-Asn(Trt)-OH synthesis process.
Reliable Deprotection and Purity
Benefit from straightforward trityl group removal using TFA, ensuring efficient deprotection and contributing to the overall high Fmoc-Asn(Trt)-OH purity of your final peptide product.
Key Applications
Peptide Synthesis
As a vital building block, it is indispensable for the construction of complex peptide sequences in research and pharmaceutical development.
Organic Synthesis
Its well-defined chemical structure makes it valuable in various organic synthesis pathways where protected amino acids are required.
Biotechnology
Used in biotechnology research for creating novel peptides with specific therapeutic or diagnostic applications.
Pharmaceutical Intermediates
Serves as a key intermediate in the production of peptide-based active pharmaceutical ingredients (APIs).