1,1,1-Trifluoroisopropanol: A Key Chiral Intermediate
Unlock the potential of advanced synthesis with this critical chiral building block.
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1,1,1-Trifluoroisopropanol
1,1,1-Trifluoroisopropanol (CAS 374-01-6) is a vital chiral intermediate, highly valued for its unique properties conferred by the trifluoromethyl group and its precise stereochemistry. Its application as a pharmaceutical intermediate and in agrochemical synthesis is paramount.
- Explore the 1,1,1-Trifluoroisopropanol pharmaceutical intermediate applications to see how it enhances drug efficacy and metabolic stability in new medicines.
- Discover efficient 1,1,1-Trifluoroisopropanol synthesis routes leveraging advanced asymmetric hydrogenation and biocatalytic reduction of trifluoroacetone.
- Understand the impact of the trifluoromethyl group drug properties, including improved lipophilicity and bioavailability, crucial for pharmaceutical development.
- Learn about CAS 374-01-6 applications in creating complex chiral molecules for both pharmaceutical and agrochemical sectors.
Key Advantages
Enhanced Efficacy
The incorporation of the trifluoromethyl moiety significantly boosts drug efficacy and metabolic stability, leading to more potent and longer-lasting therapeutic effects.
Stereochemical Precision
As a chiral building block, it allows for the precise introduction of stereochemistry, essential for the targeted activity of many pharmaceuticals and agrochemicals.
Versatile Intermediate
Its hydroxyl group serves as a reactive handle for diverse derivatizations, making it a versatile precursor for numerous fluorinated intermediates and active compounds.
Key Applications
Pharmaceutical Intermediates
Utilize 1,1,1-Trifluoroisopropanol pharmaceutical intermediate roles to create advanced drug candidates with improved pharmacokinetic profiles.
Agrochemical Synthesis
Leverage its structure in 1,1,1-Trifluoroisopropanol agrochemical synthesis for more effective and stable pesticides and herbicides.
Organic Synthesis
As a key component in organic synthesis, it facilitates the creation of complex chiral molecules with specific functionalities.
Biochemical Research
Its unique properties make it valuable for investigating enzyme mechanisms and protein interactions in biochemical studies.