1-Benzylpiperidin-3-one Hydrochloride: A Key Intermediate in Tofacitinib Synthesis and Pharmaceutical Applications
Discover the vital role of this pharmaceutical compound in drug development and chemical synthesis.
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1-Benzylpiperidin-3-one hydrochloride
This specialized chemical compound serves as a critical building block in the pharmaceutical industry, most notably as an intermediate in the synthesis of Tofacitinib, a significant drug used to treat autoimmune diseases. Its well-defined chemical structure and reactivity make it indispensable for pharmaceutical development and fine chemical production.
- As a key pharmaceutical intermediate, its synthesis pathways are crucial for efficient drug manufacturing. The exploration of 1-Benzylpiperidin-3-one hydrochloride synthesis is vital for cost-effective production.
- With a high assay of ≥95.0%, it guarantees the purity required for sensitive pharmaceutical applications, ensuring reliability in downstream processes.
- The compound's physical and chemical properties, including a melting point of 170-176°C and a density of 1.1 g/cm³, are well-characterized, aiding in its safe and effective use.
- Beyond its established role, the potential for broader applications in medicinal chemistry makes it a compound of continued interest for researchers and drug developers seeking novel therapeutic agents.
Advantages Offered by the Product
Streamlined Drug Synthesis
Utilizing 1-Benzylpiperidin-3-one hydrochloride as a Tofacitinib intermediate significantly simplifies complex drug synthesis, leading to more efficient production cycles and reduced manufacturing times.
High Purity and Reliability
The compound's guaranteed high purity (≥95.0%) ensures consistent quality and predictable results, a critical factor for pharmaceutical manufacturers relying on a trustworthy chemical intermediate.
Versatile Chemical Intermediate
Its unique chemical structure and reactivity open doors for its use in developing a wide array of medicinal chemistry compounds, supporting innovation in drug discovery and development.
Key Applications
Tofacitinib Production
This compound is an essential intermediate for the synthesis of Tofacitinib, a JAK inhibitor used in treating autoimmune diseases like rheumatoid arthritis, highlighting its importance in modern medicine.
Pharmaceutical Intermediates
As a versatile pharmaceutical intermediate, it plays a key role in the multi-step synthesis of various active pharmaceutical ingredients (APIs), supporting the development of new treatments.
Fine Chemical Synthesis
In the realm of fine chemicals, its distinct properties make it a valuable reagent for complex organic synthesis, contributing to advancements in chemical manufacturing.
Medicinal Chemistry Research
Researchers in medicinal chemistry utilize this compound as a fundamental building block to explore and design novel drug candidates with therapeutic potential.