1-Hydroxy-7-azabenzotriazole: Your Key to Efficient Peptide Synthesis
Enhance peptide coupling reactions and minimize racemization with this crucial organic synthesis reagent.
Get a Quote & SampleProduct Core Value
1-Hydroxy-7-azabenzotriazole
1-Hydroxy-7-azabenzotriazole (HOAt) is a high-performance functional reagent essential for peptide condensation. It serves as a vital additive, significantly improving the efficiency of peptide bond formation and effectively suppressing racemization, particularly when dealing with sterically challenging amino acid sequences. As a fundamental precursor for potent condensation reagents like HATU, HOAt empowers chemists in various fields, from drug discovery to biomolecular research.
- Discover the power of efficient peptide coupling, leveraging HOAt to achieve superior yields.
- Minimize racemization during peptide condensation with the reliable performance of this organic synthesis reagent.
- Explore its role as a key building block for powerful reagents like HATU, enabling complex amide bond formation.
- Benefit from its application in drug development and biomolecular research, facilitating precise chemical synthesis.
Key Advantages
Enhanced Reaction Efficiency
Achieve higher yields and faster reaction rates in your peptide synthesis by utilizing this efficient peptide coupling additive.
Racemization Suppression
Protect the stereochemical integrity of your peptides with HOAt, which is known for its effectiveness in preventing unwanted racemization during peptide condensation.
Versatile Precursor
Leverage HOAt as a fundamental raw material for creating advanced condensation reagents, broadening the scope of your synthetic capabilities.
Key Applications
Peptide Synthesis
HOAt is indispensable for efficient peptide coupling, facilitating the formation of amide bonds crucial for creating peptides used in therapeutics and research.
Drug Discovery
In the realm of small-molecule drug development, HOAt aids in synthesizing complex molecules by providing reliable amide bond formation.
Biomolecular Research
Researchers utilize HOAt for its ability to improve reaction efficiency and reduce side reactions in various biomolecular manipulation processes.
Acylation Catalysis
As an efficient acylation catalyst, HOAt plays a vital role in various organic synthesis pathways requiring precise functional group transformations.