2-Amino-5-fluoropyridine: A Crucial Intermediate for Advanced Chemical Synthesis

Discover the pivotal role of 2-Amino-5-fluoropyridine (CAS 21717-96-4) in driving innovation across pharmaceuticals, agrochemicals, and radiochemistry. Explore its synthesis and applications.

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Advantages Offered

Enhanced Bioavailability

The fluorine atom in 2-Amino-5-fluoropyridine significantly contributes to improved drug efficacy by positively influencing pharmacokinetic properties, a key consideration in medicinal chemistry.

Versatile Synthesis Intermediate

As a versatile chemical building block, it allows for diverse derivatization, enabling the creation of a wide range of sophisticated compounds for pharmaceutical and agrochemical applications.

Critical for Radiochemistry

Its utility extends to radiochemistry, particularly in PET imaging, where it can be labeled with fluorine-18 for diagnostic purposes, aiding in the study of specific biological targets.

Key Applications

Pharmaceuticals

Used as a key intermediate in the synthesis of various drugs, including peptide deformylase inhibitors and novel anticancer agents, contributing to advancements in medicine.

Agrochemicals

Essential in the synthesis of herbicides and fungicides, supporting agricultural needs by controlling pests and diseases to enhance crop yield and quality.

Radiochemistry

Applications in positron emission tomography (PET) imaging, enabling the visualization of metabolic processes and the study of specific biological targets like PSMA expression.

Organic Synthesis

Serves as a versatile building block for creating diverse derivatives through various chemical reactions, facilitating complex organic molecule development.