Exploring 2-Amino-N-(5-chloropyridin-2-yl)-5-methoxybenzamide: Synthesis and Applications
Uncover the synthesis, properties, and critical role of this compound in advanced pharmaceutical research and development.
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2-Amino-N-(5-chloropyridin-2-yl)-5-methoxybenzamide
This compound serves as a crucial building block in medicinal chemistry, particularly for the synthesis of potent Factor Xa inhibitors like Betrixaban. Its chemical structure allows for tailored modifications to enhance biological activity and pharmacokinetic profiles, making it invaluable in the development of new anticoagulant therapies and potentially other therapeutic agents.
- Synthesis pathways for 2-Amino-N-(5-chloropyridin-2-yl)-5-methoxybenzamide synthesis are well-documented, focusing on efficient amide bond formation and selective reduction methods.
- Applications of this compound in Factor Xa inhibitor development highlight its importance in cardiovascular drug discovery.
- Understanding the chemical compound structure-activity relationship is key to optimizing its derivatives for therapeutic efficacy.
- Its role as a pharmaceutical intermediate makes it a cornerstone in the synthesis of complex drug molecules.
Key Advantages
Versatile Chemical Intermediate
This compound is a versatile building block, enabling the creation of diverse molecular structures essential for medicinal chemistry research compounds.
Factor Xa Inhibition Potential
Its derivatives are recognized for their ability to inhibit Factor Xa, a critical target for developing novel anticoagulants, underscoring its role in Factor Xa inhibitor development.
Facilitates Drug Discovery
The compound's well-defined chemical properties and synthetic accessibility streamline the process of drug discovery and synthesis intermediates.
Key Applications
Pharmaceutical Intermediates
Serves as a vital precursor in the multi-step synthesis of advanced pharmaceutical agents, crucial for pharmaceutical intermediates.
Anticoagulant Research
Its derivatives are investigated for their potent anticoagulant activity, forming the basis for developing new treatments for thrombotic disorders in anticoagulant research.
Medicinal Chemistry
A fundamental tool for medicinal chemists, enabling exploration of novel therapeutic targets and drug candidates through medicinal chemistry research.
Drug Development
Plays a significant role in the preclinical and clinical stages of drug development, particularly for compounds targeting coagulation pathways within drug development.