2'-O-Methyl-5-Methyluridine: Revolutionizing Nucleic Acid Research
Unlock advanced applications in gene targeting and antimicrobial studies with this high-purity modified nucleoside.
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2'-O-Methyl-5-Methyluridine
This advanced nucleoside is instrumental in the synthesis of sophisticated oligonucleotides, including platinum-derivatized triplex-forming oligonucleotides (Pt-TFOs). These TFOs are crucial for crosslinking to specific gene strands, notably within the human androgen receptor (AR) gene, offering precise gene targeting capabilities. Beyond its role in genetic research, 2'-O-Methyl-5-Methyluridine demonstrates significant inhibitory activity against M. bovis and M. avium, highlighting its potential in developing novel antimicrobial agents. Its high purity and specific modifications make it an invaluable tool for researchers pushing the boundaries of molecular biology and therapeutic development.
- High purity essential for precise oligonucleotide synthesis, enabling advanced gene targeting.
- Used in creating Pt-TFOs to crosslink with transcribed strands in genes like the human androgen receptor (AR).
- Possesses demonstrated inhibitory activity against bacteria such as M. bovis and M. avium.
- A key building block for researchers in biomedical fields, supporting advancements in genetic research and antimicrobial development.
Advantages Provided by the Product
Enhanced Gene Targeting Specificity
Leverage the capabilities of 2'-O-methyl-5-methyluridine applications in creating highly specific Pt-TFOs for precise gene interactions.
Potential for Novel Antimicrobial Therapies
Explore the 2'-O-methyl-5-methyluridine for inhibiting M. bovis and M. avium, paving the way for new antibacterial treatments.
Facilitates Advanced Oligonucleotide Synthesis
The high purity of this nucleoside ensures successful 2'-O-methyl-5-methyluridine synthesis, critical for complex oligonucleotide structures.
Key Applications
Oligonucleotide Synthesis
Essential for the creation of modified oligonucleotides used in cutting-edge genetic research and therapeutic development, utilizing its unique structure in nucleoside for oligonucleotide synthesis.
Gene Targeting and Therapy
A critical component in forming Pt-TFOs, facilitating precise gene modifications and offering new avenues for gene targeting in research and potential therapies.
Antimicrobial Research
Demonstrates efficacy against specific bacteria, making it a valuable compound for exploring new strategies in antimicrobial research.
Biomedical Research Tool
Serves as a fundamental building block for various studies in molecular biology, contributing to advancements in understanding and manipulating biological processes.