(3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one: A Key Intermediate in Antibiotic Synthesis
Discover the crucial role of this advanced chemical intermediate in developing life-saving carbapenem and penam beta-lactam antibiotics.
Get a Quote & SampleProduct Core Value
![(3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one](https://www.nbinno.com/2025/webimg/gemini_688ad226e25de_1753928230.png)
(3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one
This compound serves as a vital chiral building block and intermediate in the synthesis of critical beta-lactam antibiotics. Its unique azetidin-2-one structure, combined with a protected ethyl group, makes it indispensable for creating complex antibiotic molecules.
- A key intermediate for thienamycin synthesis, enabling advanced drug development.
- Facilitates the synthesis of carbapenem antibiotics, offering significant therapeutic advantages.
- Acts as a versatile chiral building block for pharmaceuticals, ensuring stereospecific synthesis.
- The presence of a tert-butyldimethylsilyloxy ethyl group enhances reactivity and allows for selective chemical transformations.
Product Advantages
Enhanced Antibiotic Efficacy
Leveraging this compound in penam beta-lactam synthesis contributes to developing antibiotics with improved potency and spectrum of activity.
Streamlined Organic Synthesis
As a highly pure azetidin-2-one derivative, it simplifies complex reaction pathways in organic synthesis, reducing steps and increasing yield.
Chiral Purity for Drug Development
Its role as a chiral building block for pharmaceuticals ensures the stereochemical integrity required for biologically active compounds.
Key Applications
Antibiotic Synthesis
A fundamental component in the synthesis of carbapenem antibiotics, crucial for treating severe bacterial infections.
Pharmaceutical Intermediates
Essential for producing various pharmaceutical compounds, acting as a critical link in complex drug manufacturing processes.
Organic Synthesis
Its versatile reactivity makes it a valuable tool for chemists in developing novel molecules and optimizing synthetic routes.
Drug Discovery Research
Used extensively in R&D to explore new antibiotic candidates and improve existing ones, supporting the synthesis of carbapenem antibiotics.