High-Purity Benzonitrile Intermediate: Synthesis, Applications, and Quality Control
Explore the critical role of advanced benzonitrile derivatives in modern pharmaceutical development and research.
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4-(6-Amino-2-(4-cyanophenylamino)pyrimidin-4-yl)oxy-3,5-dimethylbenzonitrile
This high-purity benzonitrile derivative serves as a vital intermediate in the synthesis of Etravirine, a significant component in HIV treatment. Its precise chemical structure and quality standards are paramount for effective pharmaceutical manufacturing.
- Discover the essential role of this compound in Etravirine synthesis, aiding in the development of crucial HIV therapies.
- Learn about the rigorous quality control measures, including high assay purity (≥98.0%), ensuring reliability for pharmaceutical applications.
- Understand the importance of specific storage conditions to maintain the integrity of this complex chemical compound.
- Explore its potential applications beyond Etravirine, including its role as a reference standard in chemical analysis.
Key Advantages
Enhanced Pharmaceutical Efficacy
The high purity of this benzonitrile intermediate directly contributes to the efficacy and safety of the final pharmaceutical product, like Etravirine, by minimizing unwanted side reactions.
Reliable Chemical Synthesis
As a key component in the chemical synthesis process, its consistent quality ensures predictable outcomes and efficient production of critical drug molecules.
Support for Research & Development
This compound is valuable as a reference standard for analytical method development and validation, crucial for accurate detection and quantification in R&D settings.
Key Applications
Pharmaceutical Synthesis
As a critical building block, its primary application lies in the synthesis of active pharmaceutical ingredients, particularly in antiviral medications like Etravirine.
Drug Impurity Profiling
Its role extends to being a recognized impurity of Etravirine, making it essential for analytical chemists involved in drug purity testing and regulatory compliance.
Analytical Reference Standards
Used as a reference standard to develop and validate analytical methods, ensuring the accuracy of quality control processes in pharmaceutical manufacturing.
HIV Treatment Research
Its connection to Etravirine highlights its importance in research focused on novel HIV-1 NNRTIs and understanding drug resistance mechanisms.