5-Bromo-2-chloropyrimidine: A Key Pharmaceutical Intermediate
Essential building block for Macitentan synthesis, crucial for treating pulmonary arterial hypertension.
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5-Bromo-2-chloropyrimidine
As a critical pharmaceutical intermediate, 5-Bromo-2-chloropyrimidine (CAS: 32779-36-5) plays a pivotal role in the complex synthesis of Macitentan, a vital medication used in the treatment of pulmonary arterial hypertension. Its specific chemical structure makes it an ideal building block for creating the active pharmaceutical ingredient (API) of Macitentan, contributing to its therapeutic efficacy in managing this serious cardiovascular condition. The reliable supply and high purity of this chemical intermediate are paramount for the consistent production of life-saving drugs.
- Discover the precise chemical synthesis routes for Macitentan using 5-bromo-2-chloropyrimidine.
- Explore why 5-bromo-2-chloropyrimidine CAS 32779-36-5 is a preferred choice among chemical manufacturers for API synthesis.
- Learn about the importance of high-purity pharmaceutical building blocks like 5-bromo-2-chloropyrimidine for drug development.
- Understand the applications of this compound in cross-coupling reactions, vital for modern organic synthesis.
Key Advantages
High Purity for Reliable Synthesis
Ensuring a minimum purity of 98% for 5-bromo-2-chloropyrimidine guarantees the efficiency and success of complex pharmaceutical synthesis pathways, minimizing side reactions and downstream purification challenges.
Versatile Chemical Intermediate
This compound is not only integral to macitentan synthesis but also serves as a valuable reactant in various cross-coupling reactions, broadening its utility in chemical research and development.
Critical for Cardiovascular Therapies
Its role as an intermediate for macitentan highlights its significance in producing treatments for pulmonary arterial hypertension, impacting patient health globally.
Key Applications
Pharmaceutical Synthesis
Used extensively as a key intermediate in the production of active pharmaceutical ingredients (APIs), particularly for cardiovascular drugs like Macitentan, vital for treating pulmonary arterial hypertension.
Organic Chemistry Research
A valuable building block in organic synthesis, enabling various chemical transformations and reactions such as indium organometallic cross-coupling reactions.
Drug Discovery and Development
Essential for researchers in drug discovery, providing a reliable starting material for creating novel therapeutic compounds and exploring new chemical entities.
Fine Chemical Manufacturing
Supplied for manufacturing processes requiring high-purity heterocyclic compounds, ensuring quality and consistency in the final products.
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