7-Ethylcamptothecin: A Potent Topoisomerase I Inhibitor for Advanced Cancer Therapies
Exploring the cytotoxic potential and therapeutic applications of a key pharmaceutical intermediate.
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7-Ethylcamptothecin
7-Ethylcamptothecin is a highly effective cytotoxic topoisomerase I inhibitor, demonstrating significantly stronger growth-inhibiting activity against tumor cells compared to its parent compound. As the active metabolite of Irinotecan, it is crucial in understanding and developing advanced cancer therapies. Its research is vital for next-generation antineoplastic agents.
- Understanding the 7-Ethylcamptothecin synthesis and antitumor activity is key for pharmaceutical research and development.
- The 7-ethyl-10-hydroxycamptothecin mechanism of action involves inhibiting DNA topoisomerase I.
- Researchers often seek to buy 7-Ethylcamptothecin online for its potent cytotoxic activity in cancer cell line studies.
- As the active metabolite of Irinotecan, SN-38 (7-Ethylcamptothecin) offers insights into drug efficacy and resistance mechanisms.
Key Advantages
Enhanced Cytotoxicity
Possesses significantly higher cytotoxicity against tumor cells, making it a valuable component in potent drug formulations. The pursuit to buy 7-Ethylcamptothecin fuels research into more effective cancer treatments.
Active Metabolite Insight
As the active metabolite of Irinotecan (SN-38), it provides critical data for understanding drug metabolism and optimizing chemotherapy regimens, aiding the study of the 7-ethyl-10-hydroxycamptothecin mechanism of action.
Research & Development Focus
Essential for preclinical studies and the development of novel cancer therapeutics, driving innovation in antineoplastic drug discovery by providing a reliable 7-Ethylcamptothecin CAS 78287-27-1 supplier.
Key Applications
Oncology Drug Development
Used in research for developing novel antineoplastic agents and understanding cancer cell responses to topoisomerase I inhibition, reflecting the 7-Ethylcamptothecin synthesis and antitumor activity research.
Pharmaceutical Intermediate
Serves as a critical intermediate in the synthesis of complex drug molecules, contributing to the broader pharmaceutical intermediate market and research into potent compounds.
Biochemical Research Tool
Valuable for in vitro and in vivo studies investigating drug efficacy, resistance mechanisms, and the detailed 7-ethyl-10-hydroxycamptothecin mechanism of action in various cancer models.
Reference Standard
Functions as a reference standard in analytical chemistry for quality control of Irinotecan and related compounds, ensuring the integrity of pharmaceutical products.