Ajulemic Acid (CAS 137945-48-3): Properties, Applications, and Research Insights
Exploring the potent anti-inflammatory and analgesic effects of this synthetic cannabinoid analog for therapeutic applications.
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Ajulemic acid
Ajulemic acid is a synthetic analog of tetrahydrocannabinol-11-oic acid, recognized for its potent anti-inflammatory, analgesic, and anti-fibrotic properties. It distinguishes itself from THC by exhibiting minimal central nervous system activity and a favorable safety profile, making it a promising candidate for therapeutic applications.
- Experience potent analgesic and anti-inflammatory effects as supported by Ajulemic acid analgesic anti-inflammatory effects research.
- Understand the complex Ajulemic acid synthesis pathway, detailing key intermediates and reaction optimization for efficient production.
- Delve into the Ajulemic acid mechanism of action, focusing on its selective binding to PPAR-gamma and cannabinoid receptors.
- Explore Ajulemic acid preclinical studies that highlight its efficacy in treating conditions like fibrosis and arthritis.
Key Advantages
Non-Psychoactive Profile
Ajulemic acid's minimal CB1 receptor affinity translates to a lack of psychoactive effects, distinguishing it from traditional cannabinoids and improving patient tolerability in pain management applications.
Therapeutic Versatility
Its anti-inflammatory and anti-fibrotic properties make it suitable for a range of inflammatory diseases, as evidenced by ongoing research and Ajulemic acid clinical trials.
Favorable Pharmacokinetics
The compound demonstrates minimal CYP450 metabolism, reducing the risk of drug-drug interactions and offering a more predictable therapeutic profile compared to other cannabinoids.
Key Applications
Pain Management
Ajulemic acid's potent analgesic properties are explored for chronic pain conditions, offering an alternative to traditional pain relievers with a better safety profile, as seen in Ajulemic acid analgesic anti-inflammatory effects studies.
Inflammatory Diseases
Research into Ajulemic acid focuses on its ability to treat conditions like arthritis, dermatomyositis, and systemic lupus erythematosus by reducing inflammation and tissue damage.
Fibrosis Treatment
The anti-fibrotic effects of Ajulemic acid make it a candidate for treating conditions involving tissue scarring, such as pulmonary fibrosis and systemic sclerosis.
Research Tool
Its unique interaction with PPAR-gamma and cannabinoid receptors makes it a valuable tool in pharmacological research aimed at understanding inflammatory pathways and developing new therapeutic agents.