Chlorobutanol (CAS 57-15-8): Properties, Applications, and Synthesis
Discover the comprehensive role of Chlorobutanol in pharmaceuticals, cosmetics, and beyond. Explore its unique chemical properties and extensive applications.
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Chlorobutanol
Chlorobutanol (CAS 57-15-8) is a crucial organic compound valued for its potent preservative capabilities, alongside its sedative and local anesthetic properties. It serves as a vital component in ensuring the long-term stability and safety of various pharmaceutical and cosmetic formulations.
- This compound is primarily used as a preservative in pharmaceutical preparations, ensuring the integrity of multi-ingredient formulations.
- Its antibacterial and antifungal properties make it an effective agent for preventing microbial contamination in ophthalmic solutions and cosmetics.
- Chlorobutanol also exhibits sedative and hypnotic effects, similar to chloral hydrate, making it useful in certain therapeutic contexts.
- The compound's weak local anesthetic properties contribute to its use as a mild analgesic in dental applications and other topical treatments.
Key Advantages
Broad-Spectrum Antimicrobial Action
Chlorobutanol's effectiveness as a chlorobutanol preservative for eye drops stems from its ability to combat a wide range of bacteria and fungi, ensuring product safety and shelf-life.
Versatile Pharmaceutical Applications
As a key chlorobutanol pharmaceutical intermediate, it's integral to numerous drug formulations, including injectables and ophthalmic solutions, demonstrating its broad utility.
Facilitates Complex Synthesis
The synthesis of chlorobutanol from acetone and chloroform is a well-established process, providing a reliable source for this important chemical. This controlled chlorobutanol synthesis mechanism is key to its industrial availability.
Key Applications
Pharmaceutical Preservative
Chlorobutanol is widely used as an antimicrobial preservative chlorobutanol in ophthalmic and parenteral dosage forms, ensuring the microbial stability of medications.
Cosmetic Formulations
In the cosmetics industry, it functions as a preservative, safeguarding products from microbial spoilage and extending their usability.
Local Anesthetic and Analgesic
Its properties as a chlorobutanol local anesthetic make it valuable in dental applications and other topical treatments for mild pain relief.
Sedative and Hypnotic Agent
The chlorobutanol sedative hypnotic effects are leveraged in certain pharmaceutical preparations requiring CNS depression, contributing to patient comfort.
Related Technical Articles & Resources
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