Ethyl 2-(4-chloro-2-(methylthio)pyrimidin-5-yl)acetate: A Key Intermediate in Pharmaceutical Synthesis
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Ethyl 2-(4-chloro-2-(methylthio)pyrimidin-5-yl)acetate
This compound, identified by CAS 61727-34-2, is a vital ethyl ester derivative of pyrimidineacetic acid. Its primary application lies as a crucial building block in the synthesis of advanced pharmaceutical compounds, most notably as a precursor for dihydropyrrolopyrimidine-selective JAK2 inhibitors. Researchers and manufacturers rely on its specific chemical structure and purity for successful synthesis outcomes in drug development.
- Exploring the synthesis of ethyl 2-(4-chloro-2-(methylthio)pyrimidin-5-yl)acetate is critical for consistent pharmaceutical production.
- The CAS 61727-34-2 chemical intermediate offers a reliable foundation for complex organic synthesis.
- As a key JAK2 inhibitor precursor, this compound is instrumental in developing novel therapeutics.
- Ensuring high purity for pharmaceutical building blocks like this pyrimidineacetic acid ethyl ester is paramount for research efficacy.
Key Advantages
High Purity Assured
With purity levels often exceeding 97% or 98%, this intermediate guarantees reliable results in demanding organic synthesis and pharmaceutical applications, contributing to the success of your research into JAK2 inhibitors.
Versatile Pharmaceutical Intermediate
Its unique pyrimidineacetic acid ethyl ester structure makes it a versatile building block for a wide array of medicinal chemistry projects, supporting custom synthesis of pyrimidine derivatives for novel drug candidates.
Optimized Storage Conditions
Recommended storage under inert gas (nitrogen or argon) at 2-8°C ensures the stability and longevity of this compound, crucial for maintaining the integrity of your sensitive reaction processes.
Key Applications
Pharmaceutical Research
As a CAS 61727-34-2 chemical intermediate, it is extensively used in the research and development of new pharmaceutical agents, particularly those targeting specific biological pathways.
JAK2 Inhibitor Synthesis
Its role as a JAK2 inhibitor precursor makes it indispensable for the synthesis of drugs aimed at treating myeloproliferative neoplasms and other related conditions.
Organic Synthesis
This compound serves as a fundamental starting material for various complex organic synthesis projects, enabling the creation of novel heterocyclic compounds with diverse applications.
Custom Synthesis Projects
Researchers often require custom synthesis of pyrimidine derivatives, and this intermediate provides a reliable starting point for tailored molecular design and production.