Ethyl 4,4,4-Trifluorocrotonate: A Key Fluorinated Intermediate
Unlock innovation with this versatile building block for pharmaceuticals and agrochemicals.
Get a Quote & SampleProduct Core Value

Ethyl 4,4,4-trifluorocrotonate
Ethyl 4,4,4-trifluorocrotonate (CAS 25597-16-4) is a crucial chemical intermediate prized for its trifluoromethyl group. It is instrumental in the synthesis of complex organic molecules, finding significant utility in the pharmaceutical and agrochemical industries. The presence of the trifluoromethyl group enhances lipophilicity and metabolic stability, making it a valuable component in drug development. Researchers also leverage it in materials science to create advanced polymers and coatings with improved chemical resistance and durability. Its unique properties provide a competitive edge in various applications, facilitating the creation of innovative fluorinated compounds.
- This vital pharmaceutical intermediate is key for enhancing lipophilicity and metabolic stability in drug development.
- As a versatile building block, it supports the synthesis of complex organic molecules.
- Its application in agrochemical synthesis improves efficacy and environmental persistence.
- Research into the synthesis of fluorinated compounds often utilizes this compound as a primary reactant.
Key Advantages
Enhanced Efficacy
The trifluoromethyl group in this compound significantly boosts the biological activity of drug candidates, supporting effective drug development.
Versatile Synthesis
Acts as a flexible building block for chemists, enabling exploration of new reaction pathways and mechanisms in organic synthesis.
Improved Material Properties
Used in specialty polymers and coatings, it contributes to materials with superior thermal and chemical resistance, as validated by its use in advanced materials.
Key Applications
Pharmaceutical Synthesis
Serves as a critical intermediate in the development of new pharmaceuticals, leveraging its trifluoromethyl group for enhanced drug properties.
Agrochemical Development
Utilized in the synthesis of agrochemicals, where fluorine incorporation can lead to improved potency and longevity in the field.
Materials Science
Applied in the creation of advanced polymers and coatings, contributing to enhanced chemical resistance and durability.
Organic Chemistry Research
An essential tool for chemists exploring novel fluorinated organic compounds and reaction pathways.