Ethyl 5-Chloropyrazolo[1,5-a]pyrimidine-3-Carboxylate: Your Key to Advanced Pharmaceutical Synthesis
Unlock novel therapeutic solutions with this high-purity intermediate, crucial for groundbreaking drug development.
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Ethyl 5-Chloropyrazolo[1,5-a]pyrimidine-3-Carboxylate
This compound serves as a vital building block in the synthesis of advanced pharmaceutical compounds, notably as an intermediate for Ropotrectinib and other novel therapeutics. Its unique heterocyclic structure and reactive chlorine atom at the 5-position make it an ideal starting material for Structure-Activity Relationship (SAR) studies and the development of targeted therapies.
- Enabling Ropotrectinib intermediate synthesis: This compound is a critical precursor in the manufacturing pathway of Ropotrectinib, a significant drug in targeted cancer therapies.
- Facilitating Drug Discovery with Heterocyclic Building Blocks: As a versatile heterocyclic compound, it offers multiple sites for chemical modification, accelerating the discovery of new drug candidates.
- Key for Enzyme Inhibitor Development: Its derivatives have shown promise as potent inhibitors, particularly targeting enzymes like IRAK4, which are implicated in inflammatory diseases.
- Promoting Anticancer Research: The compound's potential in inducing apoptosis and inhibiting tumor growth makes it valuable for researchers in the oncology field.
Advantages You Gain
Synthetic Versatility
Leverage the reactivity of the 5-chloro group for efficient nucleophilic substitution reactions, enabling rapid exploration of diverse chemical space for drug discovery.
High Purity & Quality
Ensure reliable and reproducible research outcomes with a high-purity compound, crucial for pharmaceutical development and meeting stringent quality standards.
Targeted Therapeutic Potential
Utilize this intermediate to synthesize compounds with specific biological activities, addressing unmet needs in areas like cancer and inflammatory diseases.
Key Applications
Pharmaceutical Synthesis
Essential intermediate for the synthesis of Active Pharmaceutical Ingredients (APIs) and their precursors, including the development of targeted therapies.
Anticancer Drug Research
Serves as a foundational compound for creating novel anticancer agents that target specific pathways in cancer cell proliferation and survival.
Enzyme Inhibitor Development
Critical for synthesizing compounds that selectively inhibit key enzymes, offering therapeutic avenues for inflammatory conditions and other diseases.
Medicinal Chemistry SAR Studies
Enables systematic Structure-Activity Relationship (SAR) studies due to its functional handles, facilitating the optimization of lead compounds.