Fendizoic Acid CAS 84627-04-3: Synthesis, Pharmaceutical Applications, and Analytical Characterization
Explore the comprehensive details of Fendizoic Acid, a vital pharmaceutical intermediate for antitussive drug synthesis and advanced chemical applications.
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Fendizoic Acid
Fendizoic Acid (CAS 84627-04-3) is a critical fine chemical intermediate, primarily recognized for its role in the synthesis of levocloperastine fendizoate, a widely used antitussive agent. Its chemical structure, featuring a biphenyl backbone, a carboxylic acid group, a ketone, and a phenolic hydroxyl group, imparts unique properties essential for pharmaceutical salt formation and improved drug efficacy. Beyond its pharmaceutical applications, it serves as a reference standard for quality control and is explored for novel therapeutic uses and in advanced materials synthesis.
- Leveraging fendizoic acid pharmaceutical intermediate roles, discover its critical function in creating levocloperastine fendizoate for effective cough suppression.
- Understand the importance of fendizoic acid as a chemical reagent in various synthesis pathways, enhancing product purity and efficacy.
- Delve into the fendizoic acid synthesis processes, comparing traditional methods with modern asymmetric synthesis for improved sustainability and yield.
- Explore the fendizoic acid analytical methods, including HPLC, crucial for ensuring API quality control and meeting stringent regulatory requirements.
Product Advantages
Enhanced Pharmaceutical Formulation
The unique structure of Fendizoic Acid facilitates the formation of stable salts with active pharmaceutical ingredients, like levocloperastine, improving their physicochemical properties and bioavailability for better therapeutic outcomes.
Critical for Quality Control
As a key fendizoic acid analytical standard, it is indispensable for method development, validation, and routine quality control testing, ensuring the purity and potency of pharmaceutical products in accordance with global regulatory standards.
Versatile Synthesis Intermediate
Fendizoic acid serves as a versatile precursor in various chemical synthesis, including the creation of advanced materials and potential novel therapeutic agents, highlighting its broad utility in chemical research and development.
Key Applications
Pharmaceutical Intermediate
Used in the synthesis of Active Pharmaceutical Ingredients (APIs), most notably levocloperastine fendizoate, an antitussive agent.
Analytical Reference Standard
Essential for quality control, method development, and validation in pharmaceutical manufacturing, ensuring product purity and compliance.
Chemical Synthesis Reagent
Serves as a building block in the synthesis of novel chemical structures, including advanced materials and potential new drug candidates.
Research and Development
Investigated for new therapeutic applications, such as antiviral drug development, and used in structure-activity relationship (SAR) studies.