Fmoc-His(Trt)-OH: Your Key to Advanced Peptide Synthesis
Unlock complex peptide sequences with high-purity Fmoc-His(Trt)-OH, essential for drug discovery and biotechnology.
Get a Quote & SampleProduct Core Value
Fmoc-His(Trt)-OH
N-Fmoc-N'-trityl-L-histidine, identified by CAS 109425-51-6, is a critical protected amino acid derivative indispensable for the intricate processes of peptide synthesis. Its meticulous design, featuring the Fmoc protecting group on the alpha-amino group and the Trityl group on the imidazole ring, ensures selective deprotection and controlled coupling, thereby preventing side reactions and preserving the integrity of the peptide chain during solid-phase peptide synthesis (SPPS).
- Experience the benefit of high purity (≥98% HPLC) when you buy Fmoc-His(Trt)-OH online for your critical research and development needs.
- This essential peptide building block is a cornerstone for creating custom peptide synthesis sequences, vital for drug development projects.
- As a key Fmoc amino acid derivative, it facilitates the construction of complex peptides, making it invaluable in biotechnology research.
- The protective nature of Trityl on histidine's side chain is crucial; understanding this protecting group for histidine is key to successful peptide chain elongation.
Advantages You'll Gain
Enhanced Synthesis Control
The strategic placement of Fmoc and Trityl protecting groups in this Fmoc-His(Trt)-OH compound offers unparalleled control during peptide elongation, minimizing racemization and improving overall yield.
Accelerated Drug Discovery
As a key component for drug development, this amino acid derivative enables the efficient synthesis of novel peptide-based therapeutics, speeding up the discovery pipeline.
Reliable for Biotechnology Applications
Researchers in biotechnology rely on the consistent quality of this high purity Fmoc amino acid for accurate protein engineering and bioconjugation experiments.
Key Applications
Peptide Synthesis
This Fmoc-His(Trt)-OH is a fundamental reagent in solid phase peptide synthesis, allowing for the precise assembly of complex peptide chains with protected side chains.
Drug Development
Its role as a peptide building block is critical in the development of peptide-based pharmaceuticals targeting various diseases, from metabolic disorders to cancer treatments.
Bioconjugation
Researchers utilize this compound to create peptide conjugates for targeted drug delivery or diagnostic imaging, enhancing the specificity and efficacy of therapeutic agents.
Protein Engineering
The compound aids in the synthesis of modified proteins with tailored properties, essential for developing advanced biocatalysts or therapeutic proteins with improved stability and activity.