Fmoc-Ile-Aib-OH: Essential for Advanced Peptide Synthesis
Discover the critical role of Fmoc-Ile-Aib-OH in creating stable and biologically active peptides.
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Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH is a high-purity protected dipeptide fragment, indispensable for modern solid-phase peptide synthesis (SPPS). Its unique structure, featuring the Fmoc protecting group on the N-terminus and an alpha-aminoisobutyric acid (Aib) residue, provides enhanced stability and structural integrity to synthesized peptides.
- Leveraging Fmoc-Ile-Aib-OH for precise peptide synthesis ensures the incorporation of a stable dipeptide unit, crucial for developing complex peptide sequences.
- The Aib residue in peptides is known for its ability to induce specific secondary structures like helices, making this a valuable component for pharmaceutical intermediates in drug discovery.
- With a guaranteed purity of ≥99.0%, this compound is a reliable choice for researchers focused on Fmoc protected amino acids for SPPS.
- The applications of Fmoc-Ile-Aib-OH span across various fields, including the synthesis of peptides with therapeutic potential and complex biomolecules.
Advantages Offered
Enhanced Peptide Stability
The inclusion of the Aib residue in Fmoc-Ile-Aib-OH significantly improves the structural rigidity and stability of the resultant peptide chains, a key factor for peptide synthesis reagents with demanding applications.
Reliable Purity for Research
Ensuring a purity level of ≥99.0%, this compound is a trusted building block for researchers working on specialty amino acid derivatives for drug discovery, minimizing side reactions and ensuring reproducible results.
Streamlined Synthesis Process
As a protected dipeptide, Fmoc-Ile-Aib-OH simplifies the complex process of solid phase peptide synthesis, allowing for more efficient assembly of target peptide sequences.
Key Applications
Peptide Synthesis
Used extensively in solid-phase peptide synthesis (SPPS) as a crucial building block, enabling the efficient construction of peptide chains for various research purposes.
Drug Discovery
Serves as a key intermediate in the development of novel peptide-based therapeutics, where structural integrity and precise sequence are paramount for biological activity.
Pharmaceutical Intermediates
Its high purity and defined structure make it an ideal component for creating complex pharmaceutical intermediates, supporting the pipeline for new drug candidates.
Chemical Synthesis
A valuable reagent in broader organic synthesis, particularly for constructing molecules that require specific amino acid fragments with protected functionalities.