Fmoc-Ser(tBu)-OH: A Cornerstone in Peptide Synthesis
Unlock advanced peptide synthesis with Fmoc-Ser(tBu)-OH, a premium building block for groundbreaking research.
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Fmoc-Ser(tBu)-OH
Fmoc-Ser(tBu)-OH, scientifically known as N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-serine, is an indispensable derivative of serine utilized extensively in solid-phase peptide synthesis (SPPS). Its primary value lies in its ability to facilitate the precise incorporation of serine residues into growing peptide chains. The tert-butyl protecting group on the side chain offers crucial orthogonality, allowing for selective removal under conditions that are compatible with Fmoc chemistry, thereby minimizing unwanted side reactions and ensuring product integrity.
- High Purity for Reliable Peptide Synthesis: With a purity level typically exceeding 98%, this reagent guarantees reproducible and high-quality peptide synthesis outcomes, supporting critical research endeavors.
- Versatile Building Block for Complex Peptides: As a key component in peptide synthesis, it enables the construction of complex peptides and bioactive compounds essential for various scientific applications.
- Optimized for Fmoc-Based SPPS: Its chemical structure and protecting group strategy are perfectly aligned with Fmoc-based solid-phase peptide synthesis protocols, ensuring efficient coupling and deprotection cycles.
- Enhancing Biomolecule Modification: The hydrophobic nature of Fmoc-Ser(tBu)-OH makes it a valuable tool for researchers looking to modify peptide and protein structures, influencing their biological activity and function.
Key Advantages
Enhanced Synthesis Efficiency
Leveraging the properties of Fmoc-Ser(tBu)-OH in your peptide synthesis workflow significantly boosts efficiency and yields, crucial for timely research progress.
Uncompromised Product Purity
Achieve superior purity in your synthesized peptides. The reliable nature of this Fmoc amino acid derivative minimizes impurities, ensuring data accuracy.
Facilitates Targeted Peptide Design
The specific chemical properties of Fmoc-Ser(tBu)-OH allow researchers to design and synthesize peptides with tailored functionalities and targeted biological activities.
Key Applications
Pharmaceutical Research
Utilizing Fmoc-Ser(tBu)-OH for research is paramount in discovering new therapeutic agents and understanding disease mechanisms through novel peptide drug development.
Biotechnology
In biotechnology, this derivative is instrumental in creating custom peptides for diagnostic tools, biosensors, and various protein engineering applications.
Chemical Biology
The molecule's role in chemical biology allows for the study of biological processes at a molecular level, aiding in the understanding of protein-protein interactions.
Organic Synthesis
As a fundamental building block in organic synthesis, Fmoc-Ser(tBu)-OH is key to constructing complex organic molecules with precise stereochemistry.