Unlock Superior Pharmaceutical Formulations with Fumed Silica
Enhance powder flow, stability, and tablet uniformity with high-purity fumed silica.
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Fumed Silica
This high-purity fumed silica, identified by CAS No. 7631-86-9, is a critical excipient in the pharmaceutical industry. It acts as a highly effective glidant, enhancing powder flow properties essential for consistent tablet production and capsule filling. Its anticaking capabilities prevent powder aggregation, ensuring product integrity and shelf-life. Furthermore, it serves as an emulsion stabilizer, crucial for various liquid and semi-solid dosage forms, contributing to the overall efficacy and quality of pharmaceutical products.
- Discover the benefits of using fumed silica as a pharmaceutical excipient to improve tablet production efficiencies, ensuring consistent weight and content uniformity in your final dosage forms.
- Explore how this colloidal silicon dioxide can act as a vital glidant, reducing inter-particle friction and facilitating smoother powder flow during manufacturing processes.
- Learn about the anticaking agent properties of fumed silica, which helps maintain the free-flowing nature of powders, preventing agglomeration and ensuring ease of handling.
- Understand the role of fumed silica as an emulsion stabilizer, contributing to the consistent distribution of active ingredients in various formulations, thereby enhancing drug delivery.
Key Advantages
Enhanced Powder Flow
As a premier glidant, fumed silica significantly improves the flowability of powders and granules, a critical factor for high-speed tablet and capsule manufacturing, contributing to better weight uniformity.
Caking Prevention
Its anticaking agent properties effectively prevent the aggregation of powders, ensuring they remain free-flowing and easy to process, which is vital for maintaining product quality and process efficiency.
Formulation Stability
Fumed silica acts as an emulsion stabilizer, helping to maintain the homogeneity of formulations and ensuring uniform distribution of active pharmaceutical ingredients, thus improving drug delivery and efficacy.
Key Applications
Tablet Manufacturing
Utilized as a glidant to enhance powder flow, leading to improved tablet hardness, weight uniformity, and content uniformity, thus optimizing the tabletting operation.
Capsule Filling
Facilitates precise and efficient filling of capsules by improving the free-flow of powders and granulations, preventing segregation and ensuring consistent dosage.
Semi-Solid Formulations
Acts as an inorganic thickener and viscosity enhancer, ensuring active ingredients are uniformly distributed in semi-solid dosage forms like creams and ointments.
Liquid Formulations
Functions to thicken low-polarity media, form clear gels, and help pseudoplastic flow behavior, keeping particles in suspension and preventing sedimentation.